FLT3 抗体 (AA 500-800)
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北京 101111
Quick Overview for FLT3 抗体 (AA 500-800) (ABIN7860345)
抗原
See all FLT3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 500-800
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原理
- Flt3 / CD135 (Marker of Acute Myeloid Leukemia) Antibody
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特异性
- Stem cell tyrosine kinase (STK-1) has been cloned from a CD34+ hematopoietic stem cell enriched library and identified as the human homolog of a previously identified gene of Mouse origin designated either Flk-2 or Flt-3. The STK-1 cDNA encodes a protein of 993 amino acids with 85 % identity to Flt-3/Flk-2. STK-1 is a member of the type III receptor tyrosine kinase family that includes Kit (steel factor receptor), Fms and PDGF. STK-1 expression in blood and marrow is restricted to CD34+ cells, a population greatly enriched for hematopoietic stem/progenitor cells. STK-1 antiserum recognizes two polypeptides in these cells. The Mouse homolog of STK-1, designated Flt-3/Flk-2, is expressed at high levels in hematopoietic cells and also in neural, gonadal, hepatic and placental tissues. It has been suggested that STK-1 and its murine homolog Flt-3/Flk-2 may function as growth factor receptors on hematopoietic stem and/or progenitor cells.
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纯化方法
- 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment (around aa500-800) of human FLT3 protein (exact sequence is proprietary)
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亚型
- IgG2, lambda
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anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 930-991) antibody
FLT3 适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal 7B7C3 unconjugated
anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 62-295) antibodyFLT3 适用: 小鼠, 大鼠 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 334-543) antibodyFLT3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 335-544) antibodyFLT3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 33-64), (N-Term) antibodyFLT3 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB01544 unconjugated
anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 33-64) antibodyFLT3 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Fms-Related tyrosine Kinase 3 (FLT3) (C-Term) antibodyFLT3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 650-750) antibodyFLT3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fms-Related tyrosine Kinase 3 (FLT3) antibody (PE)FLT3 适用: 人 FACS 宿主: 小鼠 Monoclonal BV10A4 PE
anti-Fms-Related tyrosine Kinase 3 (FLT3) antibody (FITC)FLT3 适用: 人 FACS 宿主: 小鼠 Monoclonal BV10A4 FITC
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))
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别名
- Flt3
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背景
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CD135, CD135 antigen, Fetal liver kinase 2, FL cytokine receptor, Flk2, FLT-3, Flt3, FLT3_HUMAN, FMS like tyrosine kinase 3, Fms related tyrosine kinase 3, Growth factor receptor tyrosine kinase type III, Ly-72, OTTHUMP0000004234, Receptor type tyrosine protein kinase FLT3, Stem cell tyrosine kinase 1, Stk 1, STK-1, Stk1, Tyrosine protein kinase receptor FLT3,
Human brain, lymph node or MDAMB468 xenograft.
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分子量
- 160kDa
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基因ID
- 2322, 507590
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UniProt
- P36888
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途径
- RTK signaling
抗原
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