Recombinant Transferrin Receptor 抗体 (AA 50-250)
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Quick Overview for Recombinant Transferrin Receptor 抗体 (AA 50-250) (ABIN7865097)
抗原
See all Transferrin Receptor (TFRC) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 50-250
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原理
- Recombinant CD71 / Transferrin Receptor (TFRC) (Extracellular Domain) Antibody
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特异性
- It recognizes a ~90-95 kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190 kDa. This MAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant human fragment (around aa50-250) of human TFRC protein (exact sequence is proprietary)
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亚型
- IgG, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
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别名
- CD71
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背景
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Mtvr-1, p90, TFR1, TFRC transferrin receptor (p90 CD71), TRFR
Human placenta, lungs or bone marrow, PC-3 cell lysate
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分子量
- 85-95kDa (monomer), 190kDa (dimer)
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基因ID
- 7037, 529618
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UniProt
- P02786
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途径
- Transition Metal Ion Homeostasis
抗原
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