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Transferrin Receptor 抗体 (C-Term)

Name: Transferrin Receptor 抗体 (C-Term)
SKU: ABIN650772
Availability: OutOfStock

TFRC 适用: 人 FACS, WB, IHC (p) 宿主: 兔 Polyclonal RB20736 unconjugated

Western blot analysis of CD71 Antibody (C-term) (ABIN650772 and ABIN2850440) in Hela cell line lysates (35 μg/lane). (Transferrin Receptor 抗体 (C-Term))

Flow cytometric analysis of hela cells using CD71 Antibody (C-term)(bottom histogram) compared to a negative control cell (top histogram)FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. (Transferrin Receptor 抗体 (C-Term))

FACS

All lanes : Anti-CD71 Antibody (C-term) at 1:2000 dilution Lane 1: A549 whole cell lysate Lane 2: CCRF-CEM whole cell lysate Lysates/proteins at 20 μg per lane. (Transferrin Receptor 抗体 (C-Term))

Formalin-fixed and paraffin-embedded human brain tissue reacted with CD71 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (Transferrin Receptor 抗体 (C-Term))

IHC (p)

5 images

产品编号 ABIN650772

发货至: 中国

Datasheet as PDF

抗原 See all Transferrin Receptor (TFRC) 抗体

Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
抗原表位
16

15

10

7

7

7

6

6

6

5

3

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 649-677, C-Term
适用
186

76

27

7

6

4

2

2

2

1

1

1

1
人
宿主
107

101

26

1

1
兔
Compatible Secondaries
克隆类型
141

93

1
多克隆
标记
105

25

19

14

9

5

3

3

3

3

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
This Transferrin Receptor antibody is un-conjugated
应用范围
139

136

69

68

50

39

23

20

17

12

7

6

3

3

2

2

1

1

1

1

1

1

1

1
Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This CD71 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 649-677 amino acids from the C-terminal region of human CD71.

克隆位点

RB20736

亚型

Ig Fraction

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anti-Transferrin Receptor (p90, CD71) (TFRC) (AA 578-765) antibody
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anti-Transferrin Receptor (p90, CD71) (TFRC) antibody
TFRC 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Transferrin Receptor (p90, CD71) (TFRC) (AA 1-140) antibody
TFRC 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-Transferrin Receptor (p90, CD71) (TFRC) (AA 68-168) antibody
TFRC 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1E6 unconjugated

anti-Transferrin Receptor (p90, CD71) (TFRC) antibody (Biotin)
TFRC 适用: 人 FACS, IP, ICC 宿主: 小鼠 Monoclonal MEM-75 Biotin

anti-Transferrin Receptor (p90, CD71) (TFRC) (AA 608-727) antibody
TFRC 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA 宿主: 小鼠 Monoclonal 1A1B2 unconjugated

anti-Transferrin Receptor (p90, CD71) (TFRC) (AA 621-720) antibody
TFRC 适用: 人, 小鼠 FACS, WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Transferrin Receptor (p90, CD71) (TFRC) (AA 567-744) antibody
TFRC 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Transferrin Receptor (p90, CD71) (TFRC) (AA 572-757) antibody
TFRC 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:1000. WB: 1:2000. IHC-P: 1:10~50. IHC-P: 1:25. FC: 1:10~50

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

有效期

6 months
抗原

Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

别名

CD71 (TFRC 产品)

别名

Trfr antibody, LOC100219280 antibody, tfr antibody, cd71 antibody, tfr1 antibody, trfr antibody, CD71 antibody, T9 antibody, TFR antibody, TFR1 antibody, TR antibody, TRFR antibody, p90 antibody, 2610028K12Rik antibody, AI195355 antibody, AI426448 antibody, AU015758 antibody, E430033M20Rik antibody, Mtvr-1 antibody, Mtvr1 antibody, transferrin receptor antibody, TFRC antibody, Tfrc antibody, tfrc antibody

背景

Cellular uptake of iron occurs via receptor mediated endocytosis of ligand occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (,By similarity),. Useful in studies of dividing haematopoietic and tumour cell populations, and metabolic activity. A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C terminal binding site. The antigen is present on most dividing cells, including normally cycling in vivo hematopoietic progenitor cells, mitogenically stimulated cells in vitro, some primary tumor cells and most proliferating cells in vitro.The transferrin receptor has been structurally characterized as a sulfide bound dimer of identical glycoprotein subunits of 95 kDa. The transferrin receptor is not present on resting blood lymphocytes. On PBL, the receptor appears after activation. The expression of transferrin receptor is coordinately regulated with cell growth. Present on T and B cell lines. The soluble (or serum) transferrin receptor (sTfR) is a circulating truncated form of the membrane receptor protein, it is an 85 kDa glycoprotein forming in serum a 320 kDa complex with diferric transferrin.The most important clinical use of the sTfR determination is in the differential diagnosis between iron deficiency anaemia and the anaemia of chronic disease. This antibody is an indicator of proliferation activity. It also has prognostic significance when typing tumors, such as leukemias and lymphomas.

分子量

84871

基因ID

7037

NCBI登录号

NP_001121620, NP_003225

UniProt

P02786

途径

Transition Metal Ion Homeostasis