Factor VII 抗体 (AA 366-466)
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Quick Overview for Factor VII 抗体 (AA 366-466) (ABIN7860022)
抗原
See all Factor VII (F7) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 366-466
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原理
- Coagulation Factor VII / F7 Antibody
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特异性
- Hemostasis following tissue injury involves the deployment of essential plasma procoagulants (prothrombin and Factors X, IX, V and VIII), which are involved in a blood coagulation cascade that leads to the formation of insoluble Fibrin clots and the promotion of platelet aggregation. Coagulation Factor VII (serum prothrombin conversion accelerator, proconvertin, F7, Factor VII) is a 406 amino acid, vitamin K-dependent, single chain serine protease that is synthesized in the liver and circulates as an inactive precursor. Factor IX A, Factor X A, Factor XII A or Thrombin-mediated proteolytic cleavage of Factor VII at Arg 152-Ile 153 generates Factor VII A, an active serine protease composed of a catalytic heavy chain disulfide linked to a light chain, containing two EGF-like domains. Mutations at the F7 locus that lead to Factor VII deficiencies are generally asymptomatic or phenotypically uncharacterized, with hemorrhagic diathesis occurring at extremely low levels.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment (around aa 366-466) of human F7 protein
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亚型
- IgG2, kappa
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anti-Coagulation Factor VII (F7) (AA 42-169) antibody
F7 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor VII (F7) (AA 1-444) antibodyF7 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor VII (F7) (AA 1-444) antibodyF7 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor VII (F7) antibodyF7 适用: 人 IHC, ELISA, IHC (p) 宿主: 绵羊 Polyclonal unconjugated
anti-Coagulation Factor VII (F7) antibodyF7 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor VII (F7) (AA 315-433) antibodyF7 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor VII (F7) (AA 334-452) antibodyF7 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor VII (F7) (AA 302-332) antibodyF7 适用: 人 WB 宿主: 兔 Polyclonal RB54990 unconjugated
anti-Coagulation Factor VII (F7) (AA 193-447) antibodyF7 适用: Cow WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor VII (F7) (AA 334-452) antibodyF7 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal 1# unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- Factor VII (F7) (Coagulation Factor VII (F7))
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别名
- Coagulation Factor VII
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背景
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Eptacog alfa, Factor VII heavy chain, Factor VII light chain, FVII coagulation protein, Proconvertin, Serum prothrombin conversion accelerator (SPCA)
Human liver or gastric carcinoma.
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分子量
- 200/80/73/50/43kDa
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基因ID
- 2155, 36989
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途径
- Response to Growth Hormone Stimulus, Platelet-derived growth Factor Receptor Signaling
抗原
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