KRT14 抗体 (AA 351-472)
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北京 101111
Quick Overview for KRT14 抗体 (AA 351-472) (ABIN7864238)
抗原
See all KRT14 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 351-472
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原理
- Cytokeratin 14 (KRT14) (Squamous Cell Marker) Antibody
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特异性
- Cytokeratin 14 (CK14) belongs to the type I (or A or acidic) subfamily of low molecular weight keratins and exists in combination with keratin 5 (type II or B or basic). CK14 is found in basal cells of squamous epithelia, some glandular epithelia, myoepithelium, and mesothelial cells.Anti-CK14 is useful in differentiating squamous cell carcinomas from poorly differentiated epithelial tumors.Anti-CK14 is one of the specific basal markers for distinguishing between basal and non-basal subtypes of breast carcinomas. Anti-CK14 is also a good marker for differentiation of intraductal from invasive salivary duct carcinoma by the positive staining of basal cells surrounding the in-situ neoplasm as well as for differentiation of benign prostate from prostate carcinoma. Furthermore, this antibody has been useful in separating oncocytic tumors of the kidney from its renal mimics, and in identifying metaplastic carcinomas of the breast.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant human KRT14 fragment (around aa351-472) (exact sequence is proprietary)
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亚型
- IgG1, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- KRT14 (Keratin 14 (KRT14))
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别名
- Cytokeratin 14
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背景
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CK-14, Dowling Meara, ebs3, ebs4, Epidermolysis Bullosa Simplex, k14, Keratin 14, Keratin Type I Cytoskeletal 14, Koebner, krt14, NFJ
A431 or HeLa cells. Human prostate, skin or squamous cell carcinoma.
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分子量
- ~50kDa
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基因ID
- 3861, 6545380
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UniProt
- P02533
抗原
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