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Recombinant Cytokeratin 5 抗体 (AA 316-590)

This 兔 单克隆 antibody specifically detects Cytokeratin 5 in IHC. It exhibits reactivity toward 人.
产品编号 ABIN7859909
发货至: 中国
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Quick Overview for Recombinant Cytokeratin 5 抗体 (AA 316-590) (ABIN7859909)

抗原

See all Cytokeratin 5 (KRT5) 抗体
Cytokeratin 5 (KRT5) (Keratin 5 (KRT5))

抗体类型

Recombinant Antibody

适用

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宿主

  • 147
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克隆类型

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单克隆

标记

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This Cytokeratin 5 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)

克隆位点

KRT5-8814R
  • 抗原表位

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    AA 316-590

    原理

    Recombinant Cytokeratin 5 (KRT5) (Basal, Myoepithelial & Mesothelial Cell Marker) Antibody

    特异性

    This Mab recognizes a protein of 58 kDa, which is identified as Cytokeratin 5 (KRT5). This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Antibodies to KRT5 identify basal cells of squamous and glandular epithelia, yoepithelial, and mesothelium. 79oΩAnti-cytokeratin 5 has been reported useful in the differential diagnosis of metastatic carcinoma in the pleura versus epithelioid mesothelioma. Almost all squamous cell carcinomas, half of transitional carcinomas, and many undifferentiated large cell carcinomas express. 79oΩAnti-KRT5, along with anti-p63, affords a high sensitivity and specificity for squamous differentiation. Myoepithelial cells of the breast, glandular epithelia, and basal cells of the prostate are labeled with anti-KRT5. 79oΩ

    纯化方法

    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Recombinant fragment (around aa 316-590) of human Cytokeratin 5 (KRT5) protein (exact sequence is proprietary)

    亚型

    IgG, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10  mM PBS

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
  • 抗原

    Cytokeratin 5 (KRT5) (Keratin 5 (KRT5))

    别名

    Cytokeratin 5

    背景

    58 kDa Cytokeratin, DDD1, Epidermolysis Bullosa Simplex 2 (EBS2), Keratin 5, Keratin, Type II Cytoskeletal 5, Keratin-5, Type-II Cytoskeletal 5, Type-II keratin Kb5

    esophagus or bladder tissue (IHC).|Human tonsil

    分子量

    58kDa

    基因ID

    3852, 433845
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