SSTR2 抗体 (AA 300-500)
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Quick Overview for SSTR2 抗体 (AA 300-500) (ABIN7864519)
抗原
See all SSTR2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 300-500
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原理
- Somatostatin Receptor Type 2 (SSTR2) Antibody
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特异性
- SSTRs (for somatostatin receptors) represent a family of G protein-coupled receptors which mediate the diverse biological actions of somatostatin (SST). There are five distinct subtypes of SSTRs that bind two natural ligands, SST-14 and SST-28. SSTR2 gives rise to spliced variants, SSTR2A and 2B. SSTRs share common signaling pathways such as the ability to inhibit adenylyl cyclase via GTP binding proteins. Some of the subtypes are also coupled to tyrosine phosphatase (SSTR1,2), Ca2+ channels (SSTR2), Na+/H+ exchanger (SSTR1), PLA-2 (SSTR4), and MAP kinase (SSTR4). Individual target cells typically express more than one SSTR subtype and often all five isoforms. Subtypes of SSTR can form functional homo- and heterodimers.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment (around aa300-500) of human SSTR2 (exact sequence is proprietary)
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亚型
- IgG2b, lambda
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- SSTR2 (Somatostatin Receptor 2 (SSTR2))
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别名
- Somatostatin Receptor Type 2
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背景
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Somatostatin receptor type 2, SRIF-1, SRIF1, SS-2-R, SS2-R, SS2R, SST2, SSTR2
colon and liver.|Human Cerebrum and kidney. In lesser amounts in jejunum
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分子量
- 87/148 kDa
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基因ID
- 6752, 514451
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UniProt
- P30874
抗原
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