Recombinant Occludin 抗体 (AA 282-415)
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Quick Overview for Recombinant Occludin 抗体 (AA 282-415) (ABIN7864075)
抗原
See all Occludin (OCLN) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 282-415
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原理
- Recombinant Occludin (OCLN) (Tight Junctions Marker) Antibody
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特异性
- Occludin is a tetraspan integral membrane protein in epithelial and endothelial tight junction (TJ) structures that can contain two extracellular loops. The protein exists in a variety of phosphorylated forms. Phosphorylation is involved in regulating both the localization and the function of Occludin. Expression of Occludin is upregulated by polyunsaturated fatty acids, increasing trans-endothelial cell resistance and reducing cellular permeability to large molecules. The level of Occludin varies greatly depending on tissue, in brain tissue, Occludin is highly expressed at cell-cell contact sites. Non-neural tissues show lower expression and discontinuous distribution. Up-regulation of epithelial Occludin may play a role in enhancing paracellular permeability and be related to the damage to the tight junction.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant human Occludin fragment around aa 282-415 (Exact sequence is proprietary)
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亚型
- IgG, kappa
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anti-Occludin (OCLN) (AA 431-522) antibody
OCLN 适用: 人, 小鼠, Pig WB, ELISA, FACS, IHC (p), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Occludin (OCLN) (C-Term) antibodyOCLN 适用: 人, 小鼠, 大鼠, 犬, 猴 WB, IHC (p), IHC (fro) 宿主: 山羊 Polyclonal unconjugated
anti-Occludin (OCLN) (AA 423-522) antibodyOCLN 适用: 人 WB, ELISA, IP, IF 宿主: 小鼠 Monoclonal 1G7 unconjugated
anti-Occludin (OCLN) (AA 1-522) antibodyOCLN 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Occludin (OCLN) (AA 1-522) antibodyOCLN 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Occludin (OCLN) (AA 282-415) antibodyOCLN 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal OCLN-2181 unconjugated
anti-Occludin (OCLN) (AA 54-270) antibodyOCLN 适用: 人 WB, IHC, ELISA, FACS, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Occludin (OCLN) (C-Term) antibodyOCLN 适用: 人, 小鼠, 大鼠, 犬 WB, IHC, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal OC-3F10 unconjugated
anti-Occludin (OCLN) (AA 285-430) antibodyOCLN 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Occludin (OCLN) (AA 350-450) antibodyOCLN 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- Occludin (OCLN)
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别名
- Occludin
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背景
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BLCPMG, Occludin, OCLN, Phosphatase 1 regulatory subunit 115, PPP1R115, PTORCH1, Tight junction protein occludin
HepG2 cells. Human kidney.
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分子量
- 60-82kDa
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基因ID
- 100506658, 592605
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UniProt
- Q16625
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途径
- Cell-Cell Junction Organization, Hepatitis C
抗原
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