Recombinant T-Box 19 抗体 (AA 235-435)
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Quick Overview for Recombinant T-Box 19 抗体 (AA 235-435) (ABIN7859601)
抗原
See all T-Box 19 (TBX19) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 235-435
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原理
- Recombinant TBXT / T-box transcription factor T / Brachyury Antibody
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特异性
- The T-box gene family consists of members that share a unique DNA binding domain. The best characterized T-box (Tbx) gene, brachyury or T, encodes a transcription factor that plays an important role in early vertebrate development. Tbx genes are a family of developmental regulators with more than 20 members recently identified among invertebrates and vertebrates. Mutations in Tbx genes have been found to cause several human diseases. The understanding of functional mechanisms of Tbx products has come mainly from the prototypical T/brachyury protein, which is a transcription activator. The T-domain is a highly conserved DNA-binding motif originally defined in brachyury and characteristic of the Tbx family of transcription factors. The murine brachyury (T) gene is required in posterior mesoderm formation and axial development. Mutant embryos lacking T gene function are deficient in notochord differentiation and posterior mesoderm formation, but develop anterior mesoderm.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment (around aa 235-435) of human TBXT protein (exact sequence is proprietary)
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亚型
- IgG, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- T-Box 19 (TBX19)
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别名
- TBXT
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背景
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BRAC_HUMAN, Brachyury homolog, Brachyury protein, Bry, MGC104817, Protein T, SAVA, T, T brachyury homolog, T brachyury transcription factor, T Protein, T, brachyury homolog (mouse), TFT, Transcription factor T
Human chordoma tissue.
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分子量
- 47kDa
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基因ID
- 6862, 389457
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UniProt
- O15178
抗原
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