T-Box 19 抗体 (AA 200-400)
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北京 101111
Quick Overview for T-Box 19 抗体 (AA 200-400) (ABIN6945138)
抗原
See all T-Box 19 (TBX19) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 200-400
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原理
- TBXT Recombinant Antibody
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交叉反应
- 人, 小鼠
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纯化方法
- Purified by Protein A.
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免疫原
- Recombinant protein within human TBXT aa 200-400.
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亚型
- IgG
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应用备注
- WB(1:300-5000), FCM(1:20-100), IHC-P(1:200-400), IF(ICC)(1:50-200), IP(1-2 μg)
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- T-Box 19 (TBX19)
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别名
- TBXT
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背景
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Synonyms: T-box transcription factor T, TBXT, Brachyury protein
Background: TBXTis an embryonic nuclear transcription factor that binds to a specific DNA element, the palindromic T-site. It binds through a region in its N-terminus, called the T-box, and effects transcription of genes required for mesoderm formation and differentiation. The protein is localized to notochord-derived cells. Variation in this gene was associated with susceptibility to neural tube defects and chordoma. A mutation in this gene was found in a family with sacral agenesis with vertebral anomalies. Involved in the transcriptional regulation of genes required for mesoderm formation and differentiation.
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基因ID
- 6862
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UniProt
- O15178
抗原
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