Recombinant Decorin 抗体 (AA 212-336)
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Quick Overview for Recombinant Decorin 抗体 (AA 212-336) (ABIN7859540)
抗原
See all Decorin (DCN) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 212-336
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原理
- Recombinant Decorin Antibody
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特异性
- Decorin is a small leucine-rich proteoglycan (SLRP) family member that consists of a glycosaminoglycan chain-containing core protein. The core protein contains ten leucine rich repeats that contain sites for glycosylation, flanked by disulfide bond stabilizing loops. Decorin binds to Collagen Type I, II and IV in vivo and promotes the formation of fibers with variations in stability and solubility. The Decorin core protein binds to growth factors, intercellular matrix molecules, such as Fibronectin and Thrombospondin, and to the Decorin endocytosis receptor. Decorin binds to and inhibits TGF≤ and is a direct or indirect negative modulator of TGF≤ synthesis. Inhibition of Decorin core protein gene expression by the combination of IFN-≥ and TNF± may contribute to cartilage destruction that is characteristic of inflammatory joint diseases. For immunostaining, pre-incubation with chondroitinase-SBC or testicular hyaluronidase may be required to expose the epitope.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant human Decorin protein fragment (around aa212-336) (exact sequence is proprietary)
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亚型
- IgG, kappa
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anti-Decorin (DCN) (AA 31-359) antibody
DCN 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Decorin (DCN) (AA 1-359) antibodyDCN 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3H4-1F4 unconjugated
anti-Decorin (DCN) (AA 263-324) antibodyDCN 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 5E8E7 unconjugated
anti-Decorin (DCN) (AA 122-150) antibodyDCN 适用: 人, 小鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB19595 unconjugated
anti-Decorin (DCN) (Internal Region) antibodyDCN 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Decorin (DCN) antibodyDCN 适用: 人 WB, IHC (p), IP, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Decorin (DCN) (AA 31-359) antibodyDCN 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Decorin (DCN) (AA 343-359), (C-Term) antibodyDCN 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Decorin (DCN) antibodyDCN 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Decorin (DCN) (AA 31-359) antibodyDCN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- Decorin (DCN)
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别名
- Decorin
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背景
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Bone proteoglycan II, CSCD, Dermatan sulphate proteoglycans II (DSPG2), PG40, PGII, PGS2, Proteoglycan core protein, SLRR1B, Small leucine rich protein 1B
Human prostate or skin tissue (IHC). Heart, Lung, Skeletal muscle.
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分子量
- 43kDa
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基因ID
- 1634, 728830
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途径
- Glycosaminoglycan Metabolic Process
抗原
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