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LAMP1 抗体 (AA 200-400)

The 小鼠 单克隆 anti-LAMP1 antibody (Clone LAMP1-7458) (ABIN7864828) specifically detects LAMP1 in IHC. The antibody is reactive with 人 samples.
产品编号 ABIN7864828
发货至: 中国
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Quick Overview for LAMP1 抗体 (AA 200-400) (ABIN7864828)

抗原

See all LAMP1 抗体
LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This LAMP1 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)

克隆位点

LAMP1-7458
  • 抗原表位

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    AA 200-400

    原理

    CD107a / Lysosomal associated membrane protein 1 (LAMP1) Antibody

    特异性

    Lysosome-associated membrane proteins (LAMP) are glycosylated type I membrane proteins that play a role in the biogenesis of the pigment melanin. LAMP-1 (also designated CD107a) and LAMP-2 (also designated CD107b) are involved in a variety of functions, including cellular adhesion, and are thought to participate in the process of tumor invasion and metastasis. Newly synthesized LAMP-1 and LAMP-2 proteins are sorted at the trans-Golgi network and are transported intracellularly via a pathway that is distinct from the Clathrincoated vesicles used for the mannose-6 phosphate receptor. LAMP-1 is expressed on the surface of Thrombin-activated but not resting platelets, and it is thought to be involved in the adhesive, prothrombic properties of these cells. Both LAMP-1 and LAMP-2 are involved in maintaining lysosome acidity and protecting the lysosomal membranes from autodigestion, and their expression is increased in patients with lysosomal storage disorders.

    纯化方法

    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Recombinant fragment (around aa200-400) of human LAMP1 protein (exact sequence is proprietary)

    亚型

    IgG1, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
  • 抗原

    LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))

    别名

    CD107a

    背景

    CD107 antigen like family member A, LAMP1, LAMPA, LGP120, lgpA, Lysosomal membrane glycoprotein 120KD, Lysosomal Associated Membrane Protein 1, Lysosome associated membrane glycoprotein 1, OTTHUMP00000040663

    Human tonsil|kidney or prostate.|Placenta

    分子量

    120 kDa

    基因ID

    3916, 494419

    途径

    Autophagy
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