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IDO2 抗体 (AA 200-350)

This 小鼠 单克隆 antibody specifically detects IDO2 in ELISA 和 IHC. It exhibits reactivity toward 人.
产品编号 ABIN7862706
发货至: 中国
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Quick Overview for IDO2 抗体 (AA 200-350) (ABIN7862706)

抗原

See all IDO2 抗体
IDO2 (Indoleamine 2,3-Dioxygenase 2 (IDO2))

适用

  • 66
  • 12
  • 10
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1

宿主

  • 61
  • 16
  • 1
小鼠

克隆类型

  • 62
  • 16
单克隆

标记

  • 43
  • 8
  • 5
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This IDO2 antibody is un-conjugated

应用范围

  • 61
  • 31
  • 24
  • 16
  • 13
  • 13
  • 7
  • 5
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
ELISA, Immunohistochemistry (IHC)

克隆位点

IDO2-2639
  • 抗原表位

    • 15
    • 9
    • 9
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 200-350

    原理

    IDO2 / Indoleamine 2,3-dioxygenase 2 Antibody

    特异性

    IDO2 is a presumptive immunomodulatory gene based on its close structural relationship to IDO1 and its expression in a variety of antigen-presenting cell types. Both IDO1 and IDO2 will catabolize tryptophan to kynurenine. Biochemical studies indicate that both enzymes are similarly robust in catabolic activity, although the in vitro conditions required for IDO2 to manifest the same level of activity differ somewhat from IDO1. However, whether IDO2 is active as a tryptophan catabolizing enzyme in human dendritic cells has been disputed. Further work is needed to conclusively determine that IDO1 and IDO2 are similar in their preference for substrates and reaction pathways to generate product. A non-redundant function for IDO2 relative to IDO1 is suggested by their rather distinct expression patterns and response to extracellular stimuli.

    纯化方法

    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Recombinant fragment (around aa 200-350) of human IDO2 protein (exact sequence is proprietary)

    亚型

    IgG, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Antibody with azide store at 2 to 8 °C. Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    IDO2 (Indoleamine 2,3-Dioxygenase 2 (IDO2))

    别名

    IDO2

    背景

    3-dioxygenase 2, 3-dioxygenase-like protein 1, EC 1.13.11., INDOL 1, Indoleamine 2, Indoleamine 2,3 dioxygenase 2, Indoleamine 2,3 dioxygenase like 1 protein, Indoleamine pyrrole 2,3 dioxygenase like 1, Indoleamine-pyrrole 2

    Human placenta or liver.

    分子量

    47kDa

    基因ID

    169355, 676257

    UniProt

    Q6ZQW0
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