ARID1A 抗体 (AA 1900-2000)
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Quick Overview for ARID1A 抗体 (AA 1900-2000) (ABIN7859354)
抗原
See all ARID1A 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1900-2000
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原理
- ARID1A / SMARCF1 Antibody
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特异性
- The SWI-SNF complex is involved in the activation of transcription via the remodeling of nucleosome structure in an ATP-dependent manner. Brm (also designated SNF2a) and Brg-1 (also designated SNF2b) are the ATPase subunits of the mammalian SWI-SNF complex. Brm, Brg-1, Ini1 (integrase interactor 1, also designated SNF5), BAF155 (also designated SRG3) and BAF170 are thought to comprise the functional core of the SWI-SNF complex. Addition of Ini1, BAF155 and BAF170 to Brg-1 appears to increase remodeling activity. Other complex subunits, such as BAF250a (p270 or ARID1A) and BAF250b (ARID1B), are thought to play regulatory roles.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment (around aa1900-2000) of human ARID1A protein (exact sequence is proprietary)
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亚型
- IgG2b, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- ARID1A (AT Rich Interactive Domain 1A (SWI-Like) (ARID1A))
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别名
- ARID1A
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背景
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actin-dependent regulator of chromatin subfamily F member 1, ARID domain containing protein 1A, AT rich interactive domain 1A (SWI like), AT rich interactive domain containing protein 1A, B120, BAF250, BAF250A, BM029, brain protein 120, BRG1-associated factor 250a, C1ORF4, chromatin remodeling factor p250, chromosome 1 open reading frame 4, ELD, hELD, hOSA1, matrix-associated, MRD14, OSA1 nuclear protein, P270, SMARCF1, SWI-like protein, SWI/SNF complex protein p270, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily f, member 1
and PBL.|colon|Highly expressed in spleen|ovary|prostate|Small Intestine|testis|thymus
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分子量
- 165-320kDa
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基因ID
- 8289, 468972
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UniProt
- O14497
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Tube Formation
抗原
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