Recombinant VWF 抗体 (AA 1150-1250)
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Quick Overview for Recombinant VWF 抗体 (AA 1150-1250) (ABIN7859085)
抗原
See all VWF 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1150-1250
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原理
- Recombinant von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) Antibody
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特异性
- Human von Willebrand factor (VWF or factor VIII-related antigen) is a 309 kDa multimeric plasma glycoprotein, important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Von Willebrand factor also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma. Von Willebrand factor is synthesized by endothelial cells and is reported to be expressed in a number of tumors of vascular origin. IHC results aid in the classification of acute myeloid leukemia FAB type M7, angiosarcoma and epithelioid hemangioendothelioma.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment (around aa 1150-1250) of human vWF protein (exact sequence is proprietary)
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亚型
- IgG, kappa
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anti-Von Willebrand Factor (VWF) (AA 1304-1452) antibody
VWF 适用: 大鼠, 小鼠 IHC, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Von Willebrand Factor (VWF) (AA 1498-1665) antibodyVWF 适用: 小鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Von Willebrand Factor (VWF) (AA 269-367) antibodyVWF 适用: 大鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Von Willebrand Factor (VWF) (AA 1815-1939) antibodyVWF 适用: 人 IHC, WB 宿主: 小鼠 Monoclonal VWF-1465 unconjugated
anti-Von Willebrand Factor (VWF) (AA 50-150) antibodyVWF 适用: 人 IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Von Willebrand Factor (VWF) (AA 2535-2813) antibodyVWF 适用: 人 IHC, WB, FACS, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Von Willebrand Factor (VWF) antibodyVWF 适用: 人 IHC, WB, FACS, ELISA 宿主: 小鼠 Monoclonal 907CT12-1-9 unconjugated
anti-Von Willebrand Factor (VWF) (AA 351-450) antibodyVWF 适用: 人, 大鼠, 小鼠 FACS, ICC, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Von Willebrand Factor (VWF) (AA 49-230) antibodyVWF 适用: 大鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Von Willebrand Factor (VWF) (AA 1-273) antibodyVWF 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A11 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- VWF (Von Willebrand Factor (VWF))
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别名
- von Willebrand Factor
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背景
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Coagulation Factor VIII, F8VWF, von Willebrand Antigen 2, von Willebrand Disease (vWD)
Human tonsil.
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分子量
- 250kDa
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基因ID
- 7450, 440848
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UniProt
- P04275
抗原
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