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MUC13 抗体 (AA 100-300)

This 小鼠 单克隆 antibody specifically detects MUC13 in IHC. It exhibits reactivity toward 人.
产品编号 ABIN7865387
发货至: 中国
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Quick Overview for MUC13 抗体 (AA 100-300) (ABIN7865387)

抗原

See all MUC13 抗体
MUC13 (Mucin 13, Cell Surface Associated (MUC13))

适用

  • 44
  • 26
  • 12
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1

宿主

  • 41
  • 15
  • 2
  • 1
小鼠

克隆类型

  • 41
  • 18
单克隆

标记

  • 34
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This MUC13 antibody is un-conjugated

应用范围

  • 35
  • 20
  • 13
  • 13
  • 12
  • 11
  • 10
  • 5
  • 4
  • 3
  • 2
  • 1
  • 1
Immunohistochemistry (IHC)

克隆位点

MUC13-13112
  • 抗原表位

    • 15
    • 11
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 100-300

    原理

    MUC13 / Mucin 13 Antibody

    特异性

    Mucins are epithelial glycoproteins with a high content of clustered oligosaccharides that are O-glycoside linked to tandem repeat peptides rich in threonine, serine and proline. Mucin 13 (MUC13), also designated downregulated in colon cancer 1 (DRCC1), is an epithelial and hemopoietic type I membrane protein that undergoes secretion and influences gastrointestinal mucosa levels. It is most abundant in epithelial tissues of the gastrointestinal and respiratory tracts, such as large intestine and trachea, followed by kidney, small intestine, appendix and stomach. Mucin 13 is a good differentiation marker for gastrointestinal mucosa and may also indicate certain gastric tumors. It localizes to the apical membrane of both columnar and goblet cells in the gastrointestinal tract, and within goblet cell thecae. Mucin 13 is a cleaved protein, and the b subunit, containing the cytoplasmic tail, can homodimerize.

    纯化方法

    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Recombinant fragment (around aa100-300) of human MUC13 protein (exact sequence is proprietary)

    亚型

    IgG1, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
  • 抗原

    MUC13 (Mucin 13, Cell Surface Associated (MUC13))

    别名

    MUC13

    背景

    DRCC1, MUC-13

    Human colon or small intestine.

    分子量

    58kDa

    基因ID

    56667, 514227

    UniProt

    Q9H3R2
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