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TFPI2 抗体 (AA 100-235)

This 小鼠 单克隆 antibody specifically detects TFPI2 in IHC. It exhibits reactivity toward 人.
产品编号 ABIN7858943
发货至: 中国
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Quick Overview for TFPI2 抗体 (AA 100-235) (ABIN7858943)

抗原

See all TFPI2 抗体
TFPI2 (Tissue Factor Pathway Inhibitor 2 (TFPI2))

适用

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  • 21
  • 12
  • 4
  • 2
  • 2
  • 2
  • 1

宿主

  • 55
  • 18
  • 2
  • 1
小鼠

克隆类型

  • 58
  • 18
单克隆

标记

  • 48
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  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
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  • 1
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  • 1
  • 1
  • 1
  • 1
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This TFPI2 antibody is un-conjugated

应用范围

  • 40
  • 23
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  • 15
  • 13
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  • 11
  • 8
  • 4
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  • 1
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Immunohistochemistry (IHC)

克隆位点

TFPI2-13025
  • 抗原表位

    • 15
    • 11
    • 9
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
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    AA 100-235

    原理

    TFPI2 (Marker of Ovarian Carcinoma) Antibody

    特异性

    The extrinsic pathway of blood coagulation is initiated by contact of plasma factor VII with tissue factor, a cellular membrane glycoprotein that normally is segregated from the bloodstream but can be exposed after tissue injury or newly synthesized in endothelial cells or leukocytes after stimulation by endotoxin and cytokines. Inhibition of Factor VIIa tissue factor activity requires a plasma component (tissue factor pathway inhibitor (TFPI), lipoprotein-associated coagulation inhibitor (LACI) or extrinsic pathway inhibitor (EPI)) and factor Xa. TFPI directly inhibits factor Xa, and, in an Xa-dependent fashion, also inhibits the Factor VIIa tissue factor catalytic complex. TFPI is a multivalent, Kunitz-type proteinase inhibitor that circulates in association with plasma lipoproteins VLDL, LDL, and HDL. TFPI-2 (also known as placental protein 5) is a related glycoprotein that was originally isolated from human placenta.

    纯化方法

    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Recombinant fragment (around aa100-235) of human TFPI2 protein (exact sequence is proprietary)

    亚型

    IgG1, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10  mM PBS

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    TFPI2 (Tissue Factor Pathway Inhibitor 2 (TFPI2))

    别名

    TFPI2

    背景

    PP5, REF1, TFPI-2

    分子量

    27-32kDa

    基因ID

    7980, 438231

    UniProt

    P48307
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