PLK1 抗体 (AA 1-200)
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Quick Overview for PLK1 抗体 (AA 1-200) (ABIN7858666)
抗原
See all PLK1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-200
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原理
- PLK1 Antibody
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特异性
- Plk (for polo-like kinase) encodes a serine/threonine kinase that is closely related to polo and CDC5, genes that are required for passage through mitosis in Drosophila and Saccharomyces, respectively. Polo and CDC5 both code for proteins that are involved in regulating the function of the mitotic spindle. Plk protein accumulates in the cell during the S and G2 phases of the cell cycle, Plk protein content and catalytic activity peak at the onset of mitosis, followed by a rapid reduction after mitosis. Plk expression is detectable in mitotically active tissues such as colon and placenta, as well as in tumors of various origins. It has also been suggested that Plk may serve as a marker of cell proliferation.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment of human PLK1 protein (around aa 1-200) (exact sequence is proprietary)
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亚型
- IgG1, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- PLK1 (Polo-Like Kinase 1 (PLK1))
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别名
- PLK1
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背景
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Cell cycle regulated protein kinase, Polo like kinase 1, Serine/threonine protein kinase 13, Serine/threonine protein kinase PLK1, STPK13
Human tonsil|spleen or thymus.
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分子量
- 66kDa
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基因ID
- 5347, 592049
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UniProt
- P53350
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途径
- Cell Division Cycle, M Phase
抗原
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