Recombinant MSH6 抗体 (AA 1-200)
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Quick Overview for Recombinant MSH6 抗体 (AA 1-200) (ABIN7858618)
抗原
See all MSH6 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-200
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原理
- Recombinant MSH6 (DNA Mismatch Repair Protein) Antibody
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特异性
- The finding that mutations in DNA mismatch repair genes are associated with hereditary nonpolyposis colorectal cancer (HNPCC) has resulted in considerable interest in the understanding of the mechanism of DNA mismatch repair. Initially, inherited mutations in the MSH2 and MLH1 homologs of the bacterial DNA mismatch repair genes mutS and mutL were demonstrated at high frequency in HNPCC and were shown to be associated with microsatellite instability. A member of the mismatch repair family, GTBP (also designated MSH6), is an MSH2-related protein that binds to DNA containing G/T mismatches. Findings suggest that the mismatch-binding factor in human cells is composed of a heterodimer of GTBP and MSH2.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment of human MSH6 protein (around aa 1-200) (exact sequence is proprietary)
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亚型
- IgG1, kappa
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anti-MutS Homolog 6 (E. Coli) (MSH6) antibody
MSH6 适用: 人 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 3E1 unconjugated
anti-MutS Homolog 6 (E. Coli) (MSH6) (AA 374-540) antibodyMSH6 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 2E3A10 unconjugated
anti-MutS Homolog 6 (E. Coli) (MSH6) (AA 374-540) antibodyMSH6 适用: 人 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 7D9H5 unconjugated
anti-MutS Homolog 6 (E. Coli) (MSH6) (AA 931-1030) antibodyMSH6 适用: 人 WB, IF, ELISA, PLA 宿主: 小鼠 Monoclonal 1F2 unconjugated
anti-MutS Homolog 6 (E. Coli) (MSH6) (AA 374-540) antibodyMSH6 适用: 人 WB, IHC, IF, ELISA 宿主: 小鼠 Monoclonal MSH6-3091 unconjugated
anti-MutS Homolog 6 (E. Coli) (MSH6) (AA 217-395) antibodyMSH6 适用: 人, 小鼠, 猴 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 1D1C2 unconjugated
anti-MutS Homolog 6 (E. Coli) (MSH6) (N-Term) antibodyMSH6 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, Cow, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-MutS Homolog 6 (E. Coli) (MSH6) (Internal Region) antibodyMSH6 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-MutS Homolog 6 (E. Coli) (MSH6) (AA 1310-1360) antibodyMSH6 适用: 人 WB, IHC, FACS, ICC, IP 宿主: 兔 Monoclonal BLR117H unconjugated Recombinant Antibody
anti-MutS Homolog 6 (E. Coli) (MSH6) (AA 1310-1360) antibodyMSH6 适用: 人 WB, IHC, FACS, ICC, IP 宿主: 兔 Monoclonal BLR117H unconjugated Recombinant Antibody
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- MSH6 (MutS Homolog 6 (E. Coli) (MSH6))
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别名
- MSH6
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背景
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DNA mismatch repair protein Msh6, G/T mismatch-binding protein, GTBP, GTMBP, hMSH6, HNPCC5, HSAP, MSH6, mutS (E. coli) homolog 6, MutS alpha 160 kDa subunit, MutS-alpha 160 kDa subunit, p160, Sperm associated protein
Human colon carcinoma (IHC).
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分子量
- 163kDa
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基因ID
- 2956, 445052
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途径
- DNA Damage Repair, Chromatin Binding, Production of Molecular Mediator of Immune Response
抗原
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