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GCET2 抗体 (AA 1-200)

The 小鼠 单克隆 anti-GCET2 antibody is suitable to detect GCET2 in samples from 人. It has been validated for IHC.
产品编号 ABIN7862873
发货至: 中国
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Quick Overview for GCET2 抗体 (AA 1-200) (ABIN7862873)

抗原

See all GCET2 抗体
GCET2 (Germinal Center Expressed Transcript 2 (GCET2))

适用

  • 44
  • 16
  • 1

宿主

  • 43
  • 17
小鼠

克隆类型

  • 32
  • 28
单克隆

标记

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  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This GCET2 antibody is un-conjugated

应用范围

  • 25
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  • 3
Immunohistochemistry (IHC)

克隆位点

HGAL-830
  • 抗原表位

    • 15
    • 11
    • 8
    • 1
    • 1
    • 1
    • 1
    AA 1-200

    原理

    HGAL (Human Germinal Center Associated Lymphoma Marker) Antibody

    特异性

    Recognizes a protein of kDa, which is identified as HGAL. It contains a putative PDZ-interacting domain, an immunoreceptor tyrosine-based activation motif (ITAM), and two putative SH2 binding sites. In B cells, its expression is specifically induced by interleukin-4. HGAL is specifically expressed in germinal center B-cells, but is absent in mantle and marginal zone B-cells and in the inter-follicular and para-cortical regions in normal tonsils and lymph nodes. Its high degree of specificity for germinal center B-cells makes anti-HGAL an ideal marker for the detection of germinal center-derived B-cell lymphomas. HGAL expression has been used to help elucidate nodal marginal zone lymphoma (NMZL) from cases of diffuse follicle center lymphoma. Additionally, HGAL expression was shown to correlate with survival in patients with diffuse large B-cell lymphoma (DLBCL).

    纯化方法

    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Recombinant fragment (178 Amino acid residues from around aa1-200) of human HGAL protein

    亚型

    IgG1, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    GCET2 (Germinal Center Expressed Transcript 2 (GCET2))

    别名

    HGAL

    背景

    GCAT2, GCET2 germinal center expressed transcript 2, Germinal center associated lymphoma (hGAL), Germinal center B-cell-expressed transcript 2 protein, Germinal center-associated signaling and motility protein

    Daudi, Raji or U266 cells. Human lymphocytes. Human lymph node, tonsil or testis.

    分子量

    21kDa

    基因ID

    257144, 49614

    UniProt

    Q8N6F7
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