FAP 抗体 (AA 1-200)
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北京 101111
Quick Overview for FAP 抗体 (AA 1-200) (ABIN7862798)
抗原
See all FAP 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-200
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原理
- Fibroblast Activation Protein Alpha / FAP-1 Antibody
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特异性
- FAP (fibroblast activation protein) is a cell surface glycoprotein and serine protease that is expressed primarily in fetal mesenchymal tissues and epithelial cancer fibroblasts. In cancer, FAP functions to promote cellular proliferation. In embryonic development, FAP functions to remodel developing tissues. FAP acts as an integral membrane gelatinase composed of N-glycosylated proteolytically inactive subunits. FAP expression on chondrocyte membranes is upregulated by the combination of the cytokines IL-1 and OSM and has been shown to increase in osteoarthritic patients. This expression is colocalized with MMP-1 and MMP-13 as well as CD44 (variants v3 and v7/8). Mice that lack all copies of the FAP gene have been found to be fertile and to have developmental defects or change in cancer susceptibility.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment (around aa 1-200) of human FAP protein (exact sequence is proprietary)
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亚型
- IgG2c, kappa
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anti-Fibroblast Activation Protein, alpha (FAP) (AA 525-624) antibody
FAP 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1E5 unconjugated
anti-Fibroblast Activation Protein, alpha (FAP) (AA 26-264) antibodyFAP 适用: 人 IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 1H12F2 unconjugated
anti-Fibroblast Activation Protein, alpha (FAP) (AA 542-761) antibodyFAP 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Activation Protein, alpha (FAP) (AA 542-761) antibodyFAP 适用: 小鼠 WB, IHC, IP, IF/ICC 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Activation Protein, alpha (FAP) (AA 311-410) antibodyFAP 适用: 人, 小鼠, Cow WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Activation Protein, alpha (FAP) (AA 523-760) antibodyFAP 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Activation Protein, alpha (FAP) (AA 523-760) antibodyFAP 适用: 人 WB 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Fibroblast Activation Protein, alpha (FAP) (AA 15-41), (N-Term) antibodyFAP 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB40867 unconjugated
anti-Fibroblast Activation Protein, alpha (FAP) (Internal Region) antibodyFAP 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Activation Protein, alpha (FAP) (AA 26-760) antibodyFAP 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Monoclonal BLR150J unconjugated Recombinant Antibody
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- FAP (Fibroblast Activation Protein, alpha (FAP))
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别名
- Fibroblast Activation Protein Alpha
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背景
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170 kDa melanoma membrane-bound gelatinase, DPPIV, FAP, FAPA, Fibroblast activation protein alpha, Integral membrane serine protease, Seprase
Human uterus, colon or pancreas. Fibroblast specific.
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分子量
- 88kDa
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基因ID
- 2191, 654370
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UniProt
- Q12884
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途径
- Tube Formation
抗原
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