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FAP 抗体 (N-Term)

FAP 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB40867 unconjugated
产品编号 ABIN1881337
发货至: 中国
  • 抗原 See all FAP 抗体
    FAP (Fibroblast Activation Protein, alpha (FAP))
    抗原表位
    • 16
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 15-41, N-Term
    适用
    • 63
    • 33
    • 22
    • 14
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    小鼠
    宿主
    • 59
    • 11
    克隆类型
    • 57
    • 13
    多克隆
    标记
    • 44
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FAP antibody is un-conjugated
    应用范围
    • 60
    • 24
    • 19
    • 13
    • 13
    • 11
    • 10
    • 5
    • 4
    • 4
    • 4
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This Mouse Fap antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-41 amino acids from the N-terminal region of mouse Fap.
    克隆位点
    RB40867
    亚型
    Ig Fraction
    Top Product
    Discover our top product FAP Primary Antibody
  • 应用备注
    WB: 1:2000. WB: 1:500. IHC-P: 1:100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Wen, Wang, Ma, Li, Zhou, Mu, Leng, Shi, Li, Wei: "Immunotherapy targeting fibroblast activation protein inhibits tumor growth and increases survival in a murine colon cancer model." in: Cancer science, Vol. 101, Issue 11, pp. 2325-32, (2010) (PubMed).

    Santos, Jung, Aziz, Kissil, Puré: "Targeting fibroblast activation protein inhibits tumor stromagenesis and growth in mice." in: The Journal of clinical investigation, Vol. 119, Issue 12, pp. 3613-25, (2009) (PubMed).

    Kennedy, Dong, Chen, Chen: "Elevation of seprase expression and promotion of an invasive phenotype by collagenous matrices in ovarian tumor cells." in: International journal of cancer. Journal international du cancer, Vol. 124, Issue 1, pp. 27-35, (2008) (PubMed).

  • 抗原
    FAP (Fibroblast Activation Protein, alpha (FAP))
    别名
    Fap (FAP 产品)
    别名
    fap-A antibody, gene 13 antibody, FAP antibody, fapa antibody, dppiv antibody, seprase antibody, DPPIV antibody, FAPA antibody, fibroblast activation protein antibody, fibroblast activation protein alpha L homeolog antibody, fibroblast activation protein alpha antibody, fibroblast activation protein, alpha antibody, prolyl endopeptidase FAP antibody, Fap antibody, fap.L antibody, FAP antibody, fap antibody, LOC100547273 antibody
    背景
    In association with DPP4 is involved in the pericellular proteolysis of the extracellular matrix (ECM), the migration and invasion of endothelial cells into the ECM (By similarity). May have a role in tissue remodeling during development and wound healing, and contribute to invasiveness in malignant cancers.
    分子量
    87945
    NCBI登录号
    NP_032012
    UniProt
    P97321
    途径
    Tube Formation
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