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FAP 抗体 (Internal Region)

Name: FAP 抗体 (Internal Region)
Brand: antibodies-online
SKU: ABIN349584
Availability: OutOfStock

FAP 适用: 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated

Western blot using affinity purified anti-FAP antibody shows detection of FAP protein in whole cell lysates from FAP expressing HEK cells (lane 4) but not control HEK cells (lane 3). (FAP 抗体 (Internal Region))

ELISA

2 images

产品编号 ABIN349584

发货至: 中国

Datasheet as PDF

抗原 See all FAP 抗体

FAP (Fibroblast Activation Protein, alpha (FAP))
抗原表位
16

6

5

4

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1
Internal Region
适用
63

33

22

14

6

5

2

1

1

1

1

1

1

1
小鼠
宿主
59

11
兔
Compatible Secondaries
克隆类型
57

13
多克隆
标记
44

3

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This FAP antibody is un-conjugated
应用范围
60

23

19

13

13

11

11

5

4

4

4

3

1
Western Blotting (WB), ELISA

特异性

This product was affinity purified from monospecific antiserum by immunoaffinity chromatography. This antibody is known to react with mouse FAP protein. A BLAST analysis was used to suggest partial cross-reactivity with FAP from human and rat sources based on ~88% homology with the immunizing sequence. Reactivity with FAP from other sources has not been determined.

产品特性

This antibody is designed, produced, and validated as part of a collaboration with the National Cancer Institute (NCI) and is suitable for Cancer, Immunology and Nuclear Signaling research. Fibroblast Activation Protein (FAP) is expressed in the stroma of sites that are undergoing wound healing. In addition, it has recently been reported that FAP is expressed in the stroma of sites of metastatic disease. Inhibition of FAP may lead to a dramatic decrease in the number of metastatic osteosarcoma lung nodules. FAP exists as an inactive monomer and when activated forms homodimers or heterodimers with DPP4. Multiple isoforms of FAP are reported as alternative splicing products from a common gene.

纯化方法

purified

过滤

Sterile filtered

免疫原

This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region of mouse FAP protein.
Immunogen Type: Peptide

亚型

IgG

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应用备注

This affinity purified antibody has been tested for use in ELISA and western blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 88 kDa in size corresponding to FAP by western blotting in the appropriate cell lysate or extract.

说明

Gene Name: FAP

限制

仅限研究用
状态

Liquid

浓度

0.81 mg/mL

缓冲液

0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C/-20 °C

储存方法

Store vial at 4 °C prior to restoration. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is three (3) months from date of opening.

有效期

3 months
抗原

FAP (Fibroblast Activation Protein, alpha (FAP))

别名

Fibroblast Activation Protein (FAP 产品)

别名

fap-A antibody, gene 13 antibody, FAP antibody, fapa antibody, dppiv antibody, seprase antibody, DPPIV antibody, FAPA antibody, fibroblast activation protein antibody, fibroblast activation protein alpha L homeolog antibody, fibroblast activation protein alpha antibody, fibroblast activation protein, alpha antibody, prolyl endopeptidase FAP antibody, Fap antibody, fap.L antibody, FAP antibody, fap antibody, LOC100547273 antibody

背景

This antibody is designed, produced, and is suitable for Cancer, Immunology and Nuclear Signaling research. Fibroblast Activation Protein (FAP) is expressed in the stroma of sites that are undergoing wound healing. In addition, it has recently been reported that FAP is expressed in the stroma of sites of metastatic disease. Inhibition of FAP may lead to a dramatic decrease in the number of metastatic osteosarcoma lung nodules. FAP exists as an inactive monomer and when activated forms homodimers or heterodimers with DPP4. Multiple isoforms of FAP are reported as alternative splicing products from a common gene.
Synonyms: 170 kDa melanoma membrane bound gelatinase antibody, DPPIV antibody, Integral membrane serine protease antibody, FAPA antibody, Seprase antibody

基因ID

14089, 6679749

UniProt

P97321

途径

Tube Formation