Caspase 7 抗体 (AA 1-200)
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Quick Overview for Caspase 7 抗体 (AA 1-200) (ABIN7865086)
抗原
See all Caspase 7 (CASP7) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-200
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原理
- CASP7 / Caspase-7 Antibody
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特异性
- A unique family of Cysteine proteases has been described that differs in sequence, structure and substrate specificity from any previously described protease family. This family, CED-3/caspase-1, is comprised of caspase-1, caspase-2, caspase-3, caspase-4, caspase-6, caspase-7 (also designated Mch3, ICE-LAP3 or CMH-1), caspase-9 and caspase-10. CED-3/caspase-1 family members function as key components of the apoptotic machinery and act to destroy specific target proteins which are critical to cellular longevity. Poly(ADP-ribose) polymerase plays an integral role in surveying for DNA mutations and double strand breaks. Caspase-3, caspase-7 and caspase-9, but not caspase-1, have been shown to cleave the nuclear protein PARP into an apoptotic fragment. Caspase-6, but not caspase-3, has been shown to cleave the nuclear lamins which are critical to maintaining the integrity of the nuclear envelope and cellular morphology. Caspase-10 has been shown to activate caspase-3 and caspase-7 in response to apoptotic stimuli.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment (around aa1-200) of human CASP7 protein (exact sequence is proprietary)
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亚型
- IgG2b, kappa
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anti-Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) (AA 24-303) antibody
CASP7 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) (AA 207-303) antibodyCASP7 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) (AA 24-198) antibodyCASP7 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) (AA 29-198) antibodyCASP7 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 4D10B2 unconjugated
anti-Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) (AA 24-198) antibodyCASP7 适用: 人 WB, IHC, ELISA, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) (AA 24-303) antibodyCASP7 适用: 人, 大鼠 WB, IHC, ELISA, ICC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) antibodyCASP7 适用: 人, 小鼠, 大鼠, 猴, Pig, 犬, 兔, Hamster, 绵羊 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 7-1-11 unconjugated
anti-Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) (N-Term) antibodyCASP7 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) antibodyKD Validated CASP7 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB2090 unconjugated Recombinant Antibody
anti-Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) (AA 160-240) antibodyCASP7 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody w2ithout azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))
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别名
- CASP7
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背景
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Apoptotic protease MCH3, Caspase 7 apoptosis related cysteine peptidase, Caspase-7 subunit p11, CMH1, ICE LAP3, ICE-like apoptotic protease 3, LICE2, MCH3
Heart|HL60 or Jurkat cells. Human liver|liver or kidney.|spleen
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分子量
- 28-34kDa
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基因ID
- 840, 9216
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UniProt
- P55210
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途径
- Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
抗原
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