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CDC5L 抗体 (AA 1-148)

The 小鼠 单克隆 anti-CDC5L antibody is suitable to detect CDC5L in samples from 人. It has been validated for IHC 和 FACS.
产品编号 ABIN7858269
发货至: 中国
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Room 801-803
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Quick Overview for CDC5L 抗体 (AA 1-148) (ABIN7858269)

抗原

See all CDC5L 抗体
CDC5L (CDC5 Cell Division Cycle 5-Like (S. Pombe) (CDC5L))

适用

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宿主

  • 74
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小鼠

克隆类型

  • 54
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单克隆

标记

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This CDC5L antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Flow Cytometry (FACS)

克隆位点

PCRP-CDC5L-2C6
  • 抗原表位

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    AA 1-148

    原理

    CDC5L Antibody

    特异性

    Cdc5L (cell division cycle 5-like protein, pombe Cdc5-related protein) is a DNA-binding protein encoded by the human gene CDC5L. Cdc5L contains two HTH Myb-type DNA-binding domains and may shuttle between cytoplasm and nucleus. It is involved in cell cycle control and may act as a transcription activator. Cdc5L is a spliceosomal protein that is highly conserved across species. It belongs to the group of proteins that comprise the core of spliceosomal complexes and are essential for pre-mRNA splicing. Cdc5L is involved in the second catalytic step of pre-mRNA splicing, which involves cleavage at the 3' splice site and the ligation of the exons. This process releases the intact intron lariat. A chromosomal aberration involving Cdc5L is found in multicystic renal dysplasia. This aberration is caused by a translocation (t 6;19,p21;q13.1) with USF-2.

    纯化方法

    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Recombinant fragment (around aa 1-148) of human CDC5L protein (exact sequence is proprietary)

    亚型

    IgG2a, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10  mM PBS

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
  • 抗原

    CDC5L (CDC5 Cell Division Cycle 5-Like (S. Pombe) (CDC5L))

    别名

    CDC5L

    背景

    CDC5, CDC5 cell division cycle 5-like (S. pombe), Cdc5 related protein, CDC5-LIKE, Cdc5-like protein, Cdc5l, CEF1, Cell division cycle 5-like protein, dJ319D22.1, KIAA0432, PCDC5RP, Pombe Cdc5 related protein

    HeLa cells. Ubiquitously expressed in both fetal and adult tissues.

    分子量

    92kDa

    基因ID

    988, 485471

    UniProt

    Q99459

    途径

    Activation of Innate immune Response, Chromatin Binding
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