CDC5L 抗体 (AA 1-148)
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北京 101111
Quick Overview for CDC5L 抗体 (AA 1-148) (ABIN7863814)
抗原
See all CDC5L 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-148
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原理
- CDC5L Antibody
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特异性
- Cdc5L (cell division cycle 5-like protein, pombe Cdc5-related protein) is a DNA-binding protein encoded by the human gene CDC5L. Cdc5L contains two HTH Myb-type DNA-binding domains and may shuttle between cytoplasm and nucleus. It is involved in cell cycle control and may act as a transcription activator. Cdc5L is a spliceosomal protein that is highly conserved across species. It belongs to the group of proteins that comprise the core of spliceosomal complexes and are essential for pre-mRNA splicing. Cdc5L is involved in the second catalytic step of pre-mRNA splicing, which involves cleavage at the 3' splice site and the ligation of the exons. This process releases the intact intron lariat. A chromosomal aberration involving Cdc5L is found in multicystic renal dysplasia. This aberration is caused by a translocation (t 6;19,p21;q13.1) with USF-2.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment (around aa 1-148) of human CDC5L protein (exact sequence is proprietary)
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亚型
- IgG2a, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- CDC5L (CDC5 Cell Division Cycle 5-Like (S. Pombe) (CDC5L))
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别名
- CDC5L
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背景
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CDC5, CDC5 cell division cycle 5-like (S. pombe), Cdc5 related protein, CDC5-LIKE, Cdc5-like protein, Cdc5l, CEF1, Cell division cycle 5-like protein, dJ319D22.1, KIAA0432, PCDC5RP, Pombe Cdc5 related protein
HeLa cells. Ubiquitously expressed in both fetal and adult tissues.
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分子量
- 92kDa
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基因ID
- 988, 485471
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UniProt
- Q99459
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途径
- Activation of Innate immune Response, Chromatin Binding
抗原
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