Recombinant beta Catenin 抗体 (AA 1-200)
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Quick Overview for Recombinant beta Catenin 抗体 (AA 1-200) (ABIN7864665)
抗原
See all beta Catenin (CATNB) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-200
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原理
- Recombinant Catenin, beta (CTNNB1) Antibody
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特异性
- Beta-catenin associates with the cytoplasmic portion of E-cadherin, which is necessary for the function of E-cadherin as an adhesion molecule. In normal tissues, beta-catenin is localized to the membrane of epithelial cells, consistent with its role in the cell adhesion complex. In breast ductal neoplasia, beta-catenin is usually localized in cellular membranes. However, in lobular neoplasia, a marked redistribution of beta-catenin throughout the cytoplasm results in a diffuse cytoplasmic pattern. Immuno-staining of beta-catenin and E-cadherin is helps in the accurate identification of ductal and lobular neoplasms, including a distinction between low-grade ductal carcinoma in situ (DCIS) and lobular carcinoma. Additionally, some rectal and gastric adenocarcinomas demonstrate diffuse cytoplasmic beta-catenin staining and a lack of membranous staining, mimicking the staining pattern observed with lobular breast carcinomas.
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纯化方法
- 200ug/ml of Ab purified by Protein A Column.
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免疫原
- Recombinant fragment (around aa1-200) of human CTNNB1 protein (exact sequence is proprietary)
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亚型
- IgG, kappa
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anti-Catenin, beta (CATNB) (pSer33), (pSer37) antibody
CATNB 适用: 人, 小鼠, 大鼠 WB, FACS, ELISA, IF (cc), IHC (p), IF (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Catenin, beta (CATNB) (AA 661-781) antibodyCATNB 适用: 人, 小鼠, 大鼠, 斑马鱼, Pig WB, FACS, ELISA, IF (cc), IHC (p), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Catenin, beta (CATNB) (C-Term) antibodyCATNB 适用: 人, 小鼠, 大鼠, Cow, 小鸡, 犬, Pig, 兔, 绵羊, 猴, Hamster, Avian, Cat, 驴, 山羊, 豚鼠, 马 WB, IF, IHC (p), IHC (fro) 宿主: 山羊 Polyclonal unconjugated
anti-Catenin, beta (CATNB) (C-Term) antibodyCATNB 适用: 人, 斑马鱼 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Catenin, beta (CATNB) (AA 725-775) antibodyCATNB 适用: 人, 小鼠 WB, IHC, FACS, IF (p), ICC, IP 宿主: 兔 Monoclonal BLR086G unconjugated Recombinant Antibody
anti-Catenin, beta (CATNB) antibodyCATNB 适用: 人, 小鼠, 大鼠, 斑马鱼 WB, IHC, IF 宿主: 小鼠 Monoclonal unconjugated
anti-Catenin, beta (CATNB) antibodyCATNB 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 小鼠 Monoclonal 4A3H3 unconjugated
anti-Catenin, beta (CATNB) (AA 439-675) antibodyCATNB 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Catenin, beta (CATNB) (AA 439-675) antibodyCATNB 适用: 人 WB, IHC, ICC, IP 宿主: 小鼠 Monoclonal C11 unconjugated
anti-Catenin, beta (CATNB) (AA 760-781) antibodyCATNB 适用: 人, 小鼠 IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- beta Catenin (CATNB) (Catenin, beta (CATNB))
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别名
- Catenin, beta
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背景
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Cadherin associated protein, beta 1 88 kDa, Catenin beta-1, CATNB, CHBCAT, CTNNB1
Human breast carcinoma or prostate.
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分子量
- 92kDa
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基因ID
- 1499, 476018
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途径
- Peptide Hormone Metabolism
抗原
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