Recombinant Caldesmon HMW 抗体
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北京 101111
Quick Overview for Recombinant Caldesmon HMW 抗体 (ABIN7857869)
抗原
抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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Expression System
- HEK-293 Cells
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原理
- Recombinant Caldesmon, HMW (h-Caldesmon) (Smooth Muscle Marker) Antibody
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特异性
- Recognizes a protein of 150 kDa, which is identified as the high molecular weight variant of Caldesmon. Two closely related variants of human caldesmon have been identified which are different in their electrophoretic mobility and cellular distribution. The h-caldesmon variant (120 150 kDa) is predominantly expressed in smooth muscle whereas l-caldesmon (70 80 kDa) is found in non- muscle tissue and cells. Neither of the two variants has been detected in skeletal muscle. This MAb recognizes only the 150 kDa variant (h-caldesmon) in Western blots of human aortic media extracts and is unreactive with fibroblast extracts from cultivated human foreskin. Caldesmon is a developmentally regulated protein involved in smooth muscle and non-muscle contraction.
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纯化方法
- 200ug/ml of Ab produced in HEK293 cell mammalian-based expression system.
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免疫原
- Recombinant human full-length CALD1 protein
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亚型
- IgG1, kappa
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anti-Caldesmon HMW antibody
适用: 人, 大鼠 FACS, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Caldesmon HMW antibody适用: 人, 大鼠 FACS, IF, IHC (p) 宿主: 兔 Monoclonal CALD1-1424R unconjugated Recombinant Antibody
anti-Caldesmon HMW antibody适用: 人, 大鼠 FACS, IF, IHC (p) 宿主: 兔 Monoclonal CALD1-1424R unconjugated Recombinant Antibody
anti-Caldesmon HMW antibody适用: 人, 大鼠 FACS, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- Caldesmon HMW
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别名
- Caldesmon, HMW
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背景
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CAD, CALD1, Caldesmon 1 Isoform 1, Caldesmon 1 Isoform 2, Caldesmon 1 Isoform 3, Caldesmon 1 Isoform 4, Caldesmon 1 Isoform 5, CDM, HCAD, LCAD, NAG22
Blood vessels in all tissues, smooth muscle or leiomyosarcoma.
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分子量
- 150kDa
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基因ID
- 800, 490203
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UniProt
- Q05682
抗原
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