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Recombinant TCP1 alpha/CCTA 抗体 (AA 1-200)

The 小鼠 单克隆 anti-TCP1 alpha/CCTA antibody (Clone rTP63-6941) (ABIN7863557) specifically detects TCP1 alpha/CCTA in IHC. The antibody is reactive with 人 samples.
产品编号 ABIN7863557
发货至: 中国
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Quick Overview for Recombinant TCP1 alpha/CCTA 抗体 (AA 1-200) (ABIN7863557)

抗原

See all TCP1 alpha/CCTA (TCP1) 抗体
TCP1 alpha/CCTA (TCP1) (T-Complex 1 (TCP1))

抗体类型

Recombinant Antibody

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This TCP1 alpha/CCTA antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)

克隆位点

RTP63-6941
  • 抗原表位

    • 40
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    AA 1-200

    Expression System

    HEK-293 Cells

    原理

    Recombinant p63 (Squamous, Basal &, Myoepithelial Cell Marker) Antibody

    特异性

    P63 is a homolog of the tumor suppressor p53. It is identified in basal cells in the epithelial layers of a variety of tissues, including epidermis, cervix, urothelium, breast and prostate. p63 was detected in nuclei of the basal epithelium in normal prostate glands, however, it was not expressed in malignant tumors of the prostate. As a result, p63 has been reported as a useful marker for differentiating benign from malignant lesions in the prostate, particularly when used in combination with markers of high molecular weight cytokeratins and the prostate-specific marker AMACR (P504S). p63 has also been shown to be a sensitive marker for lung squamous cell carcinomas (SqCC), with a sensitivity of ~90 % . Specificity for lung SqCC, vs. lung adenocarcinoma (LADC), is approximately 80 %. In breast tissue, p63 has been identified in myoepithelial cells of normal ducts.

    纯化方法

    200ug/ml of Ab produced in HEK293 cell mammalian-based expression system.

    免疫原

    Recombinant fragment (around aa1-200) of human TP63 protein (exact sequence is proprietary)

    亚型

    IgG2a, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    TCP1 alpha/CCTA (TCP1) (T-Complex 1 (TCP1))

    别名

    p63

    背景

    Amplified in squamous cell carcinoma (AIS), Chronic ulcerative stomatitis protein (CUSP), EEC3, Keratinocyte transcription factor KET, LMS, NBP, p40, P51/P63, p53 like transcription factor, p53-related protein p63, RHS, SHFM4, TAp63alpha, TP53CP, TP53L, TP63, TP73, TP73L, Transformation-related protein 63, Trp53rp1, Trp6,3

    HEK293, lung or bladder squamous cell carcinoma tissue., MDA-MB453 or MCF7 cells. Human prostate

    分子量

    63kDa

    基因ID

    8626, 137569

    UniProt

    Q9H3D4
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