Recombinant TdT 抗体 (AA 1-100)
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Quick Overview for Recombinant TdT 抗体 (AA 1-100) (ABIN7862715)
抗原
See all TdT (DNTT) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-100
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Expression System
- HEK-293 Cells
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原理
- Recombinant TdT / DNA Nucleotidylexotransferase (Acute Lymphoblastic Leukemia Marker) Antibody
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特异性
- Terminal deoxynucleotidyl transferase (TdT) is an unusual deoxynucleotide polymerizing enzyme with a molecular weight of about 58 kDa found normally only in B- and T-cell lymphoblasts/prelymphocytes. TdT generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Rare TdT-positive cells are regularly detected in thymus and bone marrow. Typically, TdT expression in the thymus is very variable from cell to cell since it is rapidly decreased in more mature T-cells. TdT-positive cells may occasionally be found in tonsils, lymph nodes and extranodal lymphoid tissue. Immunohistochemical detection of TdT has value in classification of malignant lymphomas and acute leukemias, particularly for the identification of pre-B and pre-T acute lymphoblastic leukemia/lymphoblastic lymphoma (ALL/LBL).
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纯化方法
- 200ug/ml of Ab produced in HEK293 cell mammalian-based expression system.
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免疫原
- Recombinant fragment (around aa1-100) of human DNTT protein (exact sequence is proprietary)
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亚型
- IgG1, kappa
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anti-Deoxynucleotidyltransferase, terminal (DNTT) (AA 52-192) antibody
DNTT 适用: 人, 大鼠 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 4B10A6 unconjugated
anti-Deoxynucleotidyltransferase, terminal (DNTT) (AA 52-192) antibodyDNTT 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4B10C3 unconjugated
anti-Deoxynucleotidyltransferase, terminal (DNTT) (AA 1-110) antibodyDNTT 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4H5 unconjugated
anti-Deoxynucleotidyltransferase, terminal (DNTT) antibodyDNTT 适用: 人 IHC 宿主: 兔 Monoclonal 453R unconjugated Recombinant Antibody
anti-Deoxynucleotidyltransferase, terminal (DNTT) (AA 351-450) antibodyDNTT 适用: 人, 小鼠, 大鼠 ELISA, IHC (p), FACS, IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Deoxynucleotidyltransferase, terminal (DNTT) (Internal Region) antibodyDNTT 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Deoxynucleotidyltransferase, terminal (DNTT) (AA 1-509) antibodyDNTT 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Deoxynucleotidyltransferase, terminal (DNTT) antibodyDNTT 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB1660 unconjugated Recombinant Antibody
anti-Deoxynucleotidyltransferase, terminal (DNTT) (AA 316-509) antibodyDNTT 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Deoxynucleotidyltransferase, terminal (DNTT) antibodyDNTT 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- TdT (DNTT) (Deoxynucleotidyltransferase, terminal (DNTT))
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别名
- TdT
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背景
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Deoxynucleotidyltransferase terminal, DNTT, Nucleosidetriphosphate DNA Deoxynucleotidylexotransferase, TDT, Terminal addition enzyme, Terminal deoxynucleotidyltransferase, Terminal deoxyribonucleotidyltransferase
Human thymus. Jurkat cells.
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分子量
- 58kDa
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基因ID
- 1791, 534206
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UniProt
- P04053
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途径
- DNA Damage Repair
抗原
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