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Recombinant TGFBR1 抗体

This 小鼠 单克隆 antibody specifically detects TGFBR1 in IHC. It exhibits reactivity toward 人.
产品编号 ABIN7865491
发货至: 中国
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Quick Overview for Recombinant TGFBR1 抗体 (ABIN7865491)

抗原

See all TGFBR1 抗体
TGFBR1 (Transforming Growth Factor, beta Receptor 1 (TGFBR1))

抗体类型

Recombinant Antibody

适用

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宿主

  • 70
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小鼠

克隆类型

  • 73
  • 7
单克隆

标记

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This TGFBR1 antibody is un-conjugated

应用范围

  • 59
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Immunohistochemistry (IHC)

克隆位点

RG3E6
  • Expression System

    CHO Cells

    原理

    Recombinant Transforming Growth Factor Beta Receptor 1 (TGFBR1) Antibody

    特异性

    Transforming growth factor beta (TGFB) inhibits cell proliferation and stimulates cell differentiation. This is achieved through a receptor complex of types I and II TGFB receptors. The type II receptor is a transmembrane serine/threonine kinase which is able to bind TGFB and transactivate the type I receptor. TGFB receptors are found in all myometrial tissues and, in the kidney, they are found exclusively in renal tubular cells. In normal gastric mucosa, type I and II receptors are demonstrated in fundic glands, but not on surface mucous cells and in normal small bowel and colon, TGFB receptors are expressed in the epithelial cells of the upper crypts.

    纯化方法

    200ug/ml of Ab produced in CHO cell mammalian-based expression system.

    免疫原

    Prokaryotic recombinant protein corresponding to the external domain of the human transforming growth factor beta receptor type 1 molecule

    亚型

    IgM, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    TGFBR1 (Transforming Growth Factor, beta Receptor 1 (TGFBR1))

    别名

    Transforming Growth Factor Beta Receptor 1

    背景

    ALK5 | SKR4

    Human placenta, spleen or liver. HEK293T cells.

    分子量

    53kDa

    基因ID

    7046

    UniProt

    P36897

    途径

    Growth Factor Binding
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