Recombinant TGFBR1 抗体
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Quick Overview for Recombinant TGFBR1 抗体 (ABIN7865491)
抗原
See all TGFBR1 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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Expression System
- CHO Cells
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原理
- Recombinant Transforming Growth Factor Beta Receptor 1 (TGFBR1) Antibody
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特异性
- Transforming growth factor beta (TGFB) inhibits cell proliferation and stimulates cell differentiation. This is achieved through a receptor complex of types I and II TGFB receptors. The type II receptor is a transmembrane serine/threonine kinase which is able to bind TGFB and transactivate the type I receptor. TGFB receptors are found in all myometrial tissues and, in the kidney, they are found exclusively in renal tubular cells. In normal gastric mucosa, type I and II receptors are demonstrated in fundic glands, but not on surface mucous cells and in normal small bowel and colon, TGFB receptors are expressed in the epithelial cells of the upper crypts.
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纯化方法
- 200ug/ml of Ab produced in CHO cell mammalian-based expression system.
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免疫原
- Prokaryotic recombinant protein corresponding to the external domain of the human transforming growth factor beta receptor type 1 molecule
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亚型
- IgM, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- TGFBR1 (Transforming Growth Factor, beta Receptor 1 (TGFBR1))
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别名
- Transforming Growth Factor Beta Receptor 1
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背景
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ALK5 | SKR4
Human placenta, spleen or liver. HEK293T cells.
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分子量
- 53kDa
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基因ID
- 7046
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UniProt
- P36897
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途径
- Growth Factor Binding
抗原
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