Laminin gamma 1 抗体
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北京 101111
Quick Overview for Laminin gamma 1 抗体 (ABIN7857806)
抗原
See all Laminin gamma 1 (LAMC1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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Expression System
- CHO Cells
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原理
- Laminin, gamma 1 (LAMC1) Antibody
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特异性
- Laminins are large hetero-trimeric, non-collagenous glycoproteins composed of alpha, beta, and gamma chains. This MAb reacts with laminin B2/1 chain of ~210 kDa and does not cross-react with other basement membrane components or fibronectin. Its specificity was established by immunoprecipitation and immunofluorescence of human skeletal muscle and kidney with laminin chain-specific MAbs. Epithelial sheets in vivo are separated from the mesenchymal elements of the stroma by a thin layer of a specialized type of extracellular matrix termed the basement membrane (BM). This structure consists of individual components, some of which are ubiquitous in BMs and some are not. The ubiquitous ones comprise laminin (LN), entactin/nidogen (EN), collagen type IV (CIV), and large heparan sulfate proteoglycan (HSPG), which interact specifically with each other to form a continuous and regular BM. Alterations of BM integrity, from local discontinuities up to complete loss, are described in many types of human and animal epithelial neoplasms. This MAb stains uniformly all human and murine basement membranes.
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纯化方法
- 200ug/ml of Ab produced in CHO cell mammalian-based expression system.
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免疫原
- Recombinant human full-length LAMC1 protein
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亚型
- IgG, kappa
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anti-Laminin, gamma 1 (LAMC1) (all Isoforms) antibody
LAMC1 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Laminin, gamma 1 (LAMC1) (AA 1300-1609) antibodyLAMC1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Laminin, gamma 1 (LAMC1) (AA 1-38) antibodyLAMC1 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal M1 unconjugated
anti-Laminin, gamma 1 (LAMC1) antibodyKD Validated LAMC1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB5925 unconjugated Recombinant Antibody
anti-Laminin, gamma 1 (LAMC1) (AA 521-772) antibodyLAMC1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Laminin, gamma 1 (LAMC1) (AA 1-38) antibodyLAMC1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E6-B4 unconjugated
anti-Laminin, gamma 1 (LAMC1) (N-Term) antibodyLAMC1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Laminin, gamma 1 (LAMC1) antibodyLAMC1 适用: 小鼠 宿主: 兔 Polyclonal unconjugated
anti-Laminin, gamma 1 (LAMC1) (AA 1333-1607) antibodyLAMC1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Laminin, gamma 1 (LAMC1) (AA 1566-1579) antibodyLAMC1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- Laminin gamma 1 (LAMC1) (Laminin, gamma 1 (LAMC1))
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别名
- Laminin, gamma 1
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背景
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LAMB2, LAMC1, Laminin B2 chain, Laminin gamma 1, Laminin gamma 1 chain
Normal colon or carcinomas.
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分子量
- 210kDa
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基因ID
- 3915
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UniProt
- P11047
抗原
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