Recombinant ABCC3 抗体
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Quick Overview for Recombinant ABCC3 抗体 (ABIN7857729)
抗原
See all ABCC3 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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Expression System
- CHO Cells
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原理
- Recombinant MRP3 (Multidrug Resistance-Associated Protein 3) Antibody
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特异性
- The human multidrug resistance-associated protein (MRP) gene family contains at least 6 members designated MRP-1 to 6. MRP3 is a 190 to 200 kD integral membrane protein which is an organic anion transporter effective in transporting chemotherapeutic drugs such as MTX, etoposide and teniposide. Northern blotting of various human tissues has indicated MRP3 to be expressed in liver, colon, pancreas and at lower levels in the kidney. In liver, MRP3 is localized to the basolateral membrane of hepatocytes and is not associated with the canalicular membrane. MRP3 is also thought to play a role in bile production and secretion in the liver.
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纯化方法
- 200ug/ml of Ab produced in CHO cell mammalian-based expression system.
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免疫原
- Recombinant prokaryotic fusion protein corresponding to a region of the cytoplasmic domains between transmembrane domains 11 and 12 of the MRP3 molecule
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亚型
- IgG2b, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- ABCC3 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 3 (ABCC3))
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别名
- MRP3
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背景
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ABC31, ATP-binding cassette sub-family C member 3 (ABCC3), Canalicular multispecific organic anion transporter 2 (CMOAT2), MLP2, MOATD, Multi-specific organic anion transporter D, Multidrug resistance-associated protein 3
Human bowel, pancreas or adrenal gland.
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分子量
- 169/137/55/32/65kDa
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基因ID
- 8714, 463421
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UniProt
- O15438
抗原
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