ABCC3 抗体 (AA 815-957)
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- 抗原 See all ABCC3 抗体
- ABCC3 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 3 (ABCC3))
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抗原表位
- AA 815-957
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This ABCC3 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Staining Methods (StM)
- 纯化方法
- Purified by Protein A/G
- 免疫原
- Recombinant fragment (around aa 815-957) of human MRP3 (ABCC3) protein (exact sequence is proprietary)
- 克隆位点
- ABCC3-2971
- 亚型
- IgG1 kappa
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anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 3 (ABCC3) (AA 849-963) antibody
ABCC3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A2F6 unconjugated
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 3 (ABCC3) (AA 899-925) antibodyABCC3 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB22384 unconjugated
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 3 (ABCC3) (Middle Region) antibodyABCC3 适用: 人, 大鼠, 犬, 豚鼠, 马, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 3 (ABCC3) (AA 1291-1523) antibodyABCC3 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 3 (ABCC3) (Internal Region) antibodyABCC3 适用: 人, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 3 (ABCC3) (AA 906-933), (Middle Region) antibodyABCC3 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 3 (ABCC3) antibodyABCC3 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 3 (ABCC3) (AA 827-953) antibodyABCC3 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 3 (ABCC3) antibodyABCC3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 3 (ABCC3) (AA 684-733) antibodyABCC3 适用: 人, 犬, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Positive Control: Pancreas.
Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- 有效期
- 24 months
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- 抗原
- ABCC3 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 3 (ABCC3))
- 别名
- ABCC3 (ABCC3 产品)
- 别名
- ABC31 antibody, EST90757 antibody, MLP2 antibody, MOAT-D antibody, MRP3 antibody, cMOAT2 antibody, 1700019L09Rik antibody, Mlp2 antibody, Mrp3 antibody, ATP binding cassette subfamily C member 3 antibody, ATP-binding cassette, sub-family C (CFTR/MRP), member 3 antibody, ABCC3 antibody, Abcc3 antibody
- 背景
- The two members of the large family of ABC transporters known to confer multidrug resistance in human cancer cells are the MDR1 P-glycoprotein and the multidrug-resistance protein MRP1. MRP1 is an integral membrane protein that contains an MDR-like core, an N-terminal membrane-bound region and a cytoplasmic linker, and it is expressed in various cerebral cells, as well as in lung, testis and peripheral blood. The MRP gene family also includes MRP2, which is alternatively designated cMOAT (for canalicular multispecific organic anion transporter) and MRP3, which are both conjugate export pumps exp- ressed predominantly in hepatocytes. MRP2 localizes exclusively to the apical membrane and is constitutively expressed at a high level in normal liver cells. Conversely, MRP3 localizes to the basolateral membrane where it also medi- ates the transport of the organic anion S-(2,4-dinitrophenyl-) glutathione toward the basolateral side of the membrane. MRP3 is normally expressed at comparatively lower levels than MRP2 and increases only when secretion across the apical membrane by MRP2 is impaired.
- 分子量
- 169/137/55/32/65kDa
- 基因ID
- 8714
- UniProt
- O15438
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