Recombinant Ret Proto-Oncogene 抗体 (C-Term)
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Quick Overview for Recombinant Ret Proto-Oncogene 抗体 (C-Term) (ABIN7865342)
抗原
See all Ret Proto-Oncogene (RET) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- C-Term
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Expression System
- CHO Cells
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原理
- Recombinant RET Proto-oncogene (Medullary Thyroid Carcinoma Marker) Antibody
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特异性
- The ret-proto-oncogene encodes a cell surface glycoprotein belonging to the tyrosine-kinase receptor family. Three main splice variants have been identified. Immunoreactivity of the ret-proto-oncogene in normal tissue has been found in Schwann cells, sympathetic ganglion, adrenal medulla, astrocytes and cortical neurons.
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纯化方法
- 200ug/ml of Ab produced in CHO cell mammalian-based expression system.
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免疫原
- Prokaryotic recombinant fusion protein corresponding to the extreme C-terminal cytoplasmic region of the human ret oncoprotein
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亚型
- IgG1, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- Ret Proto-Oncogene (RET)
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别名
- RET Proto-oncogene
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背景
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Cadherin family member 12 (CDHF12), Cadherin related family member 16 (CDHR16), ELKS, HSCR1, Hydroxyaryl protein kinase, MEN2A, MEN2B, MTC1, Multiple endocrine neoplasia and medullary thyroid carcinoma 1, Oncogene RET, Proto-oncogene c-Ret, Proto-oncogene tyrosine-protein kinase receptor ret, PTC, RET, RET ELE1, RET51, RET9
Human brain, breast, colon or prostate carcinoma.
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分子量
- 150kDa (precursor), 170kDa (Mature)
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基因ID
- 5979, 350321
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UniProt
- P07949
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途径
- RTK signaling, Dopaminergic Neurogenesis, Regulation of Cell Size, Tube Formation
抗原
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