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ICOS 抗体 (AA 51-150)

ICOS 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN742380
发货至: 中国
  • 抗原 See all ICOS 抗体
    ICOS (Inducible T-Cell Co-Stimulator (ICOS))
    抗原表位
    • 14
    • 9
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 51-150
    适用
    • 81
    • 23
    • 23
    • 6
    宿主
    • 70
    • 17
    • 2
    • 1
    克隆类型
    • 67
    • 23
    多克隆
    标记
    • 38
    • 12
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ICOS antibody is un-conjugated
    应用范围
    • 58
    • 29
    • 28
    • 23
    • 13
    • 12
    • 7
    • 7
    • 6
    • 6
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    This antibody may also have a secondary cross-reactivity with AP-1 complex-associated regulatory protein due to a 77 % non-contiguous sequence similarity in the corresponding immunogen region.
    交叉反应
    预测反应
    Mouse,Rat,Pig
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human ICOS
    亚型
    IgG
    Top Product
    Discover our top product ICOS Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    ICOS (Inducible T-Cell Co-Stimulator (ICOS))
    别名
    ICOS/CD278 (ICOS 产品)
    别名
    ICOS antibody, AILIM antibody, CCLP antibody, CRP-1 antibody, H4 antibody, Ly115 antibody, CD278 antibody, CVID1 antibody, Ailim antibody, inducible T-cell costimulator antibody, inducible T cell co-stimulator antibody, inducible T-cell co-stimulator antibody, ICOS antibody, LOC100232284 antibody, Icos antibody
    背景

    Synonyms: AILIM, CD278, CVID1, Inducible T-cell costimulator, Activation-inducible lymphocyte immunomediatory molecule, ICOS

    Background: Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes (By similarity).

    基因ID
    29851
    UniProt
    Q9Y6W8
    途径
    Cancer Immune Checkpoints
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