CD163 抗体 (AA 1001-1121) (FITC)
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北京 101111
Quick Overview for CD163 抗体 (AA 1001-1121) (FITC) (ABIN741577)
抗原
See all CD163 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1001-1121
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交叉反应
- 犬, 人, 小鼠, Pig, 大鼠
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预测反应
- Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human CD163/M130
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亚型
- IgG
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anti-CD163 (CD163) (AA 1001-1121) antibody
CD163 适用: 人 WB, FACS, ELISA, ICC, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-CD163 (CD163) (AA 43-196) antibodyCD163 适用: 人 IHC, ELISA, ISt, Coat, StM 宿主: 小鼠 Monoclonal M130-2162 unconjugated
anti-CD163 (CD163) (AA 43-196) antibodyCD163 适用: 人 WB, IHC, ISt, StM 宿主: 小鼠 Monoclonal M130-1210 unconjugated
anti-CD163 (CD163) (AA 42-259) antibodyCD163 适用: 人, 小鼠 WB, IHC, FACS, ELISA 宿主: 小鼠 Monoclonal 7G5E2 unconjugated
anti-CD163 (CD163) (AA 697-972) antibodyCD163 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD163 (CD163) antibodyCD163 适用: 人 WB, FACS, IP, IHC (fro) 宿主: 小鼠 Monoclonal GHI-61 unconjugated
anti-CD163 (CD163) (AA 47-201) antibodyCD163 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-CD163 (CD163) (AA 1092-1109), (C-Term) antibodyCD163 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-CD163 (CD163) (AA 693-939) antibodyCD163 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD163 (CD163) (AA 43-196) antibodyCD163 适用: 人 IHC 宿主: 小鼠 Monoclonal 163M unconjugated
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应用备注
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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: "Interleukin-18 Amplifies Macrophage Polarization and Morphological Alteration, Leading to Excessive Angiogenesis." in: Frontiers in immunology, Vol. 9, pp. 334, (2019) (PubMed).
: "Deletion of JNK2 prevents vitamin-D-deficiency-induced hypertension and atherosclerosis in mice." in: The Journal of steroid biochemistry and molecular biology, Vol. 177, pp. 179-186, (2017) (PubMed).
: "Vitamin D deficiency induces high blood pressure and accelerates atherosclerosis in mice." in: PLoS ONE, Vol. 8, Issue 1, pp. e54625, (2013) (PubMed).
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: "Interleukin-18 Amplifies Macrophage Polarization and Morphological Alteration, Leading to Excessive Angiogenesis." in: Frontiers in immunology, Vol. 9, pp. 334, (2019) (PubMed).
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- CD163
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别名
- Cd163/M130
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背景
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Synonyms: M13, MM13, Scavenger receptor cysteine-rich type 1 protein M13, Hemoglobin scavenger receptor, CD163, M130
Background: Acute phase-regulated receptor involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. Binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH -dependent manner. Exhibits a higher affinity for complexes of hemoglobin and multimeric haptoglobin of HP*1F phenotype than for complexes of hemoglobin and dimeric haptoglobin of HP*1S phenotype. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1. Isoform 3 exhibits the higher capacity for ligand endocytosis and the more pronounced surface expression when expressed in cells. After shedding, the soluble form (sCD163) may play an anti-inflammatory role, and may be a valuable diagnostic parameter for monitoring macrophage activation in inflammatory conditions.
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基因ID
- 9332
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UniProt
- Q86VB7
抗原
-
