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CD163 抗体 (AA 43-196)

CD163 适用: 人 WB, IHC, ISt, StM 宿主: 小鼠 Monoclonal M130-1210 unconjugated
产品编号 ABIN6941114
发货至: 中国
  • 抗原 See all CD163 抗体
    CD163
    抗原表位
    • 16
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    • 2
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    • 1
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    AA 43-196
    适用
    • 128
    • 50
    • 30
    • 29
    • 20
    • 5
    • 4
    • 1
    宿主
    • 109
    • 43
    • 1
    小鼠
    克隆类型
    • 93
    • 59
    • 1
    单克隆
    标记
    • 55
    • 18
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    • 4
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    • 3
    • 3
    • 3
    • 3
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    • 1
    • 1
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    This CD163 antibody is un-conjugated
    应用范围
    • 110
    • 71
    • 51
    • 37
    • 27
    • 26
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    • 20
    • 15
    • 5
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    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunostaining (ISt), Staining Methods (StM)
    特异性
    This MAb recognizes a protein of 140 kDa, identified as CD163. It has been identified as an acute phase-regulated transmembrane protein whose function is to mediate the endocytosis of haptoglobin-hemoglobin complexes. This receptor is expressed on the surface of monocytes with low expression and on tissue macrophages, histiocytes with high expression.Staining with anti-CD163 has been helpful to distinguish synovial macrophages from synovial intimal fibroblasts in rheumatoid arthritis, where its specificity for macrophages was found to be superior to that of anti-CD68. Increased levels of CD163 were also detected in patients with microbial infections and myelomonocytic leukemias. Anti-CD163 is of considerable value for selective identification of monocytes and macrophages at a certain stage of differentiation and is suitable for diagnosing myelomonocytic or monocytic leukaemia and neoplasms of true histiocytic origin. CD163 is positive in skin (histiocytes), gut, Kupffer cells, a few alveolar macrophages, macrophages in the placenta, and in macrophages in inflamed tissues including tumor tissue.
    纯化方法
    Purified by Protein A/G
    免疫原
    Recombinant human CD163 fragment (around aa 43-196) (Exact sequence is proprietary)
    克隆位点
    M130-1210
    亚型
    IgG2b kappa
    Top Product
    Discover our top product CD163 Primary Antibody
  • 应用备注

    Positive Control: HPBL cells. Skin, Spleen, Lung, Placenta or Histiocytoma.

    Known Application: Western Blot (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0 for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    10 mM PBS with0.05 % BSA & 0.05 % azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-80 °C
    储存方法
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    有效期
    24 months
  • 抗原
    CD163
    别名
    CD163 (CD163 产品)
    别名
    DMBT1 antibody, CD163 antibody, CD163v2 antibody, CD163v3 antibody, M130 antibody, MM130 antibody, deleted in malignant brain tumors 1 protein-like antibody, CD163 molecule antibody, CD163 antigen antibody, LOC426820 antibody, CD163 antibody, Cd163 antibody
    分子量
    140kDa
    基因ID
    9332
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