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KISS1R 抗体 (AA 139-157) (Cy5)

This anti-KISS1R antibody is a 兔 多克隆 antibody detecting KISS1R in WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN741184
发货至: 中国

Quick Overview for KISS1R 抗体 (AA 139-157) (Cy5) (ABIN741184)

抗原

See all KISS1R 抗体
KISS1R (KISS1 Receptor (KISS1R))

适用

  • 45
  • 33
  • 31
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 55
  • 12

克隆类型

  • 55
  • 12
多克隆

标记

  • 44
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This KISS1R antibody is conjugated to Cy5

应用范围

  • 44
  • 30
  • 24
  • 23
  • 13
  • 13
  • 6
  • 3
  • 3
  • 2
  • 2
Western Blotting (WB)
  • 抗原表位

    • 11
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 139-157

    交叉反应

    人, 小鼠, 大鼠

    预测反应

    Dog,Sheep,Pig,Guinea Pig

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human KiSS1 receptor

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    KISS1R (KISS1 Receptor (KISS1R))

    别名

    Kiss1 Receptor

    背景

    Synonyms: HH8, CPPB1, GPR54, AXOR12, KISS-1R, HOT7T175, KiSS-1 receptor, G-protein coupled receptor 54, G-protein coupled receptor OT7T175, Hypogonadotropin-1, Kisspeptins receptor, Metastin receptor, KISS1R

    Background: Receptor for metastin (kisspeptin-54 or kp-54), a C-terminally amidated peptide of KiSS1. KiSS1 is a metastasis suppressor protein that suppresses metastases in malignant melanomas and in some breast carcinomas without affecting tumorigenicity. The metastasis suppressor properties may be mediated in part by cell cycle arrest and induction of apoptosis in malignant cells. The receptor is essential for normal gonadotropin-released hormone physiology and for puberty. The hypothalamic KiSS1/KISS1R system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood. The receptor is also probably involved in the regulation and fine-tuning of trophoblast invasion generated by the trophoblast itself. Analysis of the transduction pathways activated by the receptor identifies coupling to phospholipase C and intracellular calcium release through pertussis toxin-insensitive G(q) proteins.

    基因ID

    84634

    UniProt

    Q969F8
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