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Nitrotyrosine 抗体

The 小鼠 单克隆 anti-Nitrotyrosine antibody (Clone EM-30) (ABIN7833437) specifically detects Nitrotyrosine in WB, IHC (fro) 和 IHC (p).
产品编号 ABIN7833437
发货至: 中国
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北京 101111
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Nitrotyrosine 抗体 (ABIN7833437)

抗原

See all Nitrotyrosine 抗体
Nitrotyrosine

适用

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宿主

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小鼠

克隆类型

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单克隆

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This Nitrotyrosine antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

EM-30
  • 原理

    Anti-Nitrotyrosine (mouse monoclonal) (clone EM-30)

    交叉反应 (详细)

    Nitrotyrosine

    免疫原

    NO2-Tyr-CH2-Thyroglobulin

    亚型

    IgG1
  • 应用备注

    (IHC) paraffin: 10 μg/mL, positive tissue: colon cancer epithelium, prostate hyperplasia. (IHC) frozen sections: 10 μg/mL, positive tissue: colon cancer epithelium, prostate hyperplasia. (WB): positive control: NO2-BSA, NO2-HSA.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Immunoglobulin purified on Protein A.

    注意事项

    Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube,Do not freeze

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on the label. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
  • 抗原

    Nitrotyrosine

    物质类

    Chemical

    背景

    Background: Nitrotyrosine can be detected in proteins from a variety of tissues, usually in association with pathological conditions. Reaction of nitric oxide with superoxide produces peroxynitrite, which can undergo heterolytic cleavage into nitronium and hydroxyl ions. Nitration of tyrosine residues by nitronium ion forms nitrotyrosine groups in the respective proteins. Nitrotyrosine is thus a marker for inflammation-associated tissue damage.

    Additional information: This antibody detects nitrotyrosine group in biological material, It can be used as a marker for peroxynitrite formation in particular tissues

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