Nitrotyrosine 抗体
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北京 101111
Quick Overview for Nitrotyrosine 抗体 (ABIN7833437)
抗原
See all Nitrotyrosine 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Nitrotyrosine (mouse monoclonal) (clone EM-30)
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交叉反应 (详细)
- Nitrotyrosine
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免疫原
- NO2-Tyr-CH2-Thyroglobulin
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亚型
- IgG1
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应用备注
- (IHC) paraffin: 10 μg/mL, positive tissue: colon cancer epithelium, prostate hyperplasia. (IHC) frozen sections: 10 μg/mL, positive tissue: colon cancer epithelium, prostate hyperplasia. (WB): positive control: NO2-BSA, NO2-HSA.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Immunoglobulin purified on Protein A.
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注意事项
- Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube,Do not freeze
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on the label. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
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- Nitrotyrosine
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物质类
- Chemical
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背景
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Background: Nitrotyrosine can be detected in proteins from a variety of tissues, usually in association with pathological conditions. Reaction of nitric oxide with superoxide produces peroxynitrite, which can undergo heterolytic cleavage into nitronium and hydroxyl ions. Nitration of tyrosine residues by nitronium ion forms nitrotyrosine groups in the respective proteins. Nitrotyrosine is thus a marker for inflammation-associated tissue damage.
Additional information: This antibody detects nitrotyrosine group in biological material, It can be used as a marker for peroxynitrite formation in particular tissues
抗原
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