IL4 Receptor 抗体 (AA 201-300)
Quick Overview for IL4 Receptor 抗体 (AA 201-300) (ABIN740565)
抗原
See all IL4 Receptor (IL4R) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 201-300
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交叉反应
- 人, 小鼠
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预测反应
- Rat,Pig,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human IL4R
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亚型
- IgG
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IF(IHC-P) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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Mast cells boost myeloid-derived suppressor cell activity and contribute to the development of tumor-favoring microenvironment." in: Cancer immunology research, Vol. 3, Issue 1, pp. 85-95, (2015) (PubMed).
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Mast cells boost myeloid-derived suppressor cell activity and contribute to the development of tumor-favoring microenvironment." in: Cancer immunology research, Vol. 3, Issue 1, pp. 85-95, (2015) (PubMed).
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- IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))
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别名
- IL4R
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背景
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Synonyms: CD124, IL4RA, IL-4RA, Interleukin-4 receptor subunit alpha, IL-4 receptor subunit alpha, IL-4R subunit alpha, IL-4R-alpha, IL4R, 582J2.1
Background: Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2. Soluble IL4R (sIL4R) inhibits IL4-mediated cell proliferation and IL5 up-regulation by T-cells.
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基因ID
- 3566
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UniProt
- P24394
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途径
- JAK/STAT Signaling, Positive Regulation of Immune Effector Process
抗原
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