MCAM 抗体
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北京 101111
Quick Overview for MCAM 抗体 (ABIN7828827)
抗原
See all MCAM 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Purified Anti-Human CD146 Antibody[P1H12]
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纯化方法
- >98%, Protein A/G purified
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纯度
- >98 %
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免疫原
- Recombinant Human CD146 protein
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亚型
- IgG1, kappa
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应用备注
- FCM 2 μg/mL(0.5x106-1x106 cells)
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限制
- 仅限研究用
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浓度
- ≥ 1 mg/mL
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缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.05 % non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
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有效期
- 12 months
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- MCAM (Melanoma Cell Adhesion Molecule (MCAM))
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别名
- CD146
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背景
- CD146,cell surface glycoprotein MUC18,MUC18,A32 antigen,CD 146,CD146 antigen,Cell surface glycoprotein P1H12,Gicerin,Melanoma adhesion molecule,Melanoma associated antigen A32,Melanoma associated antigen MUC18,Melanoma associated glycoprotein MUC18,melanoma cell adhesion molecule,Melanoma-associated antigen A32,Melanoma-associated antigen MUC18,MelCAM,MUC 18,S endo 1,S endo 1 endothelial associated antigen,S-endo 1 endothelial-associated antigen,MUC,cell surface glycoprotein MUC,MCAM,CD146,MUC18,cell surface glycoprotein MUC18,S-endo,MCAM,Mel-CAM,Endo-CAM,Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration. Cat.No. Product Name Clone No. E-AB-F14170P Purified Anti-Human CD146 Antibody[AA98] AA98 IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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UniProt
- P43121
抗原
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