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MCAM 抗体

The 小鼠 单克隆 anti-MCAM antibody (Clone P1H12) (ABIN7828827) specifically detects MCAM in FACS. The antibody is reactive with 人 samples.
产品编号 ABIN7828827
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for MCAM 抗体 (ABIN7828827)

抗原

See all MCAM 抗体
MCAM (Melanoma Cell Adhesion Molecule (MCAM))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This MCAM antibody is un-conjugated

应用范围

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Flow Cytometry (FACS)

克隆位点

P1H12
  • 原理

    Purified Anti-Human CD146 Antibody[P1H12]

    纯化方法

    >98%, Protein A/G purified

    纯度

    >98 %

    免疫原

    Recombinant Human CD146 protein

    亚型

    IgG1, kappa
  • 应用备注

    FCM 2 μg/mL(0.5x106-1x106 cells)

    限制

    仅限研究用
  • 浓度

    ≥ 1 mg/mL

    缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.05 % non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

    有效期

    12 months
  • 抗原

    MCAM (Melanoma Cell Adhesion Molecule (MCAM))

    别名

    CD146

    背景

    CD146,cell surface glycoprotein MUC18,MUC18,A32 antigen,CD 146,CD146 antigen,Cell surface glycoprotein P1H12,Gicerin,Melanoma adhesion molecule,Melanoma associated antigen A32,Melanoma associated antigen MUC18,Melanoma associated glycoprotein MUC18,melanoma cell adhesion molecule,Melanoma-associated antigen A32,Melanoma-associated antigen MUC18,MelCAM,MUC 18,S endo 1,S endo 1 endothelial associated antigen,S-endo 1 endothelial-associated antigen,MUC,cell surface glycoprotein MUC,MCAM,CD146,MUC18,cell surface glycoprotein MUC18,S-endo,MCAM,Mel-CAM,Endo-CAM,Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration. Cat.No. Product Name Clone No. E-AB-F14170P Purified Anti-Human CD146 Antibody[AA98] AA98 IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

    UniProt

    P43121
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