CCR6 抗体
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北京 101111
Quick Overview for CCR6 抗体 (ABIN7828696)
抗原
See all CCR6 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Purified Anti-Human CD196/CCR6 Antibody[G034E3]
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纯化方法
- >98%, Protein A/G purified
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纯度
- >98 %
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免疫原
- Recombinant Human CD196 protein
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亚型
- IgG2b, kappa
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anti-Chemokine (C-C Motif) Receptor 6 (CCR6) antibody
CCR6 适用: 人 ELISA, WB, FACS 宿主: 小鼠 Monoclonal 7C6D9 unconjugated
anti-Chemokine (C-C Motif) Receptor 6 (CCR6) (AA 201-300) antibodyCCR6 适用: 人, 小鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 6 (CCR6) (C-Term) antibodyCCR6 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 6 (CCR6) (AA 322-374) antibodyCCR6 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 6 (CCR6) (N-Term) antibodyCCR6 适用: 人, 小鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 6 (CCR6) antibodyCCR6 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 6 (CCR6) antibodyCCR6 适用: 人 FACS 宿主: Human, 兔 Chimeric DMC477 unconjugated Fc fragment Recombinant Antibody
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应用备注
- FCM 2 μg/mL(0.5x106-1x106 cells)
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限制
- 仅限研究用
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浓度
- ≥ 1 mg/mL
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缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.05 % non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
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有效期
- 12 months
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- CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))
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别名
- CCR6
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背景
- DCR,DRY,GPR,CKRL,STRL,CKR-L,CMKBR,GPRCY,CC-CKR,C-C CKR,CCR,CCR6,BN-1,C-C CKR-6,CC-CKR-6,CCR-6,CD196,CKR-L3,CKRL3,CMKBR6,DCR2,DRY6,GPR29,GPRCY4,STRL22,BN 1,BN1,C C chemokine receptor type 6,C C CKR 6,CC chemokine receptor type 6,C-C chemokine receptor type 6,CC CKR 6,CC R6,CCCKR6,CCR 6,CD 196,CD196 antigen,Chemokine (C C motif) receptor 6,Chemokine (C C) receptor 6,Chemokine (CC motif) receptor 6,Chemokine (CC) receptor 6,Chemokine receptor 6,Chemokine receptor like 3,Chemokine receptor-like 3,CKR 6,CKR L3,CKR6,CMKBR 6,DCR 2,DRY 6,G protein coupled receptor 29,GPR 29,GPR CY4,GPRCY 4,GPR-CY4,G-protein coupled receptor 29,LARC receptor,Seven transmembrane receptor lymphocyte 22,STRL 22,CCR6, also known as CD196, is a chemokine receptor that is expressed on immature dendritic cells, B lymphocytes, and memory T cells. CCR6 binds CCL20, although members of the β defensin family also bind CCR6 with a lower affinity. CCR6 positive cells, and its ligand CCL20, have been detected in numerous organs, especially the secondary lymphoid organ. CCL20 is selectively made by the follicle-associated epithelium (FAE) overlying Peyers Patches (PPs) and isolated lymphoid follicles (ILFs). CCL20 contributes to the recruitment of CCR6-expressing B cells to these structures. In humans, CCR6 can function to mediate arrest of T cells on dermal endothelial cells and is highly expressed on T cells resident in both normal and psoriatic skin. CCR6 and/or CCL20 have been implicated in the pathogenesis of rheumatoid arthritis and inflammatory bowel disease. Human T cells that are able to produce IL-17 express CCR6. It suggests that CCL20 and CCR6 have a role in inflammatory diseases by recruiting Th17 cells to target tissues. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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UniProt
- P51684
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途径
- cAMP Metabolic Process
抗原
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