Recombinant CLCN2 抗体
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北京 101111
Quick Overview for Recombinant CLCN2 抗体 (ABIN7828687)
抗原
See all CLCN2 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant ClC-2 Monoclonal Antibody
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纯化方法
- Protein A purified
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免疫原
- Recombinant human ClC-2 fragment
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亚型
- IgG, kappa
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应用备注
- WB 1:500-1:1000,IHC 1:50-1:100
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- CLCN2 (Chloride Channel 2 (CLCN2))
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别名
- ClC-2
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背景
- CIC,CLCN,EJM,EGI,CLC,ECA,CLCN2,CIC-2,CLC2,ECA2,ECA3,EGI11,EGI3,EGMA,EJM6,EJM8,LKPAT,clC-2,ClC-2 (chloride channel protein 2) is a transmembrane protein and functions as a voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume, membrane potential stabilization, signal transduction and transepithelial transport. ClC-2 is highly expressed in adrenal gland and involved in the regulation of aldosterone production. The opening of CLCN2 channels at hyperpolarized membrane potentials in the glomerulosa causes cell membrane depolarization, activation of voltage-gated Ca2+ channels and increased expression of aldosterone synthase, the rate-limiting enzyme for aldosterone biosynthesis. Defects in this gene may be a cause of certain epilepsies. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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分子量
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Calculated MW: 99 kDa
Observed MW: 94/99 kDa The actual band is not consistent with the expectation.
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UniProt
- P51788
抗原
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