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Recombinant ZNF259 抗体

The 兔 单克隆 anti-ZNF259 antibody is suitable to detect ZNF259 in samples from 人. It has been validated for WB.
产品编号 ABIN7828682
发货至: 中国
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Quick Overview for Recombinant ZNF259 抗体 (ABIN7828682)

抗原

See all ZNF259 (znf259) 抗体
ZNF259 (znf259) (Zinc Finger Protein 259 (znf259))

抗体类型

Recombinant Antibody

适用

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宿主

  • 43
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克隆类型

  • 33
  • 14
单克隆

标记

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This ZNF259 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

A747
  • 原理

    Recombinant ZPR1 Monoclonal Antibody

    纯化方法

    Protein A purified

    亚型

    IgG, kappa
  • 应用备注

    WB 1:1000

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

    有效期

    12 months
  • 抗原

    ZNF259 (znf259) (Zinc Finger Protein 259 (znf259))

    别名

    ZPR1

    背景

    ZPR,MGC,Zinc finger protein,Zinc finger protein ZPR,ZNF,ZPR1,ZNF259,MGC110983,Zinc finger protein 259,Zinc finger protein ZPR1,ZNF 259,The zinc finger protein ZPR1 (ZNF259) binds to epidermal growth factor receptor (EGFR) and is localized to both cytoplasm and nucleus. The zinc fingers found in ZPR1 and the tyrosine kinase domain of EGFR mediate the interaction between ZPR1 and the receptor (1). ZPR1 translocates from the cytoplasm to nucleus following mitogen (i.e. EGF) stimulation (2,3). ZPR1 also interacts with translation elongation factor eEF1A in vivo following EGF treatment (3). The interaction between the zinc finger protein and elongation factor is important for cell proliferation. Cells lacking ZPR1 exhibit abnormal nucleolar function, suggesting that ZPR1 is required for cell viability and nucleolar function in dividing cells (3). ZPR1 knockout mice exhibit significant neurodegeneration, and reduced or altered expression of ZPR1 may contribute to spinal muscular atrophy, a disorder characterized by degeneration of spinal cord neurons (4). Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

    分子量

    Calculated MW: 51 kDa

    Observed MW: 53 kDa The actual band is not consistent with the expectation.

    UniProt

    O75312
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