Recombinant ERBB4 抗体
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北京 101111
Quick Overview for Recombinant ERBB4 抗体 (ABIN7828663)
抗原
See all ERBB4 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant HER4/ErbB4 Monoclonal Antibody
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纯化方法
- Protein A purified
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免疫原
- Recombinant human HER4/ErbB4 fragment
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亚型
- IgG, kappa
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应用备注
- IHC 1:200-1:1000,IF 1:50
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- ERBB4 (V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4))
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别名
- HER4/ErbB4
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背景
- ALS,HER,ERBB,Proto-oncogene-like protein c-ErbB,Receptor tyrosine-protein kinase erbB,Tyrosine kinase-type cell surface receptor HER,p180erbB,HER4/ErbB,ALS19,HER4,p180erbB4,ERBB4,HER4/ErbB4,Proto-oncogene-like protein c-ErbB-4,Receptor tyrosine-protein kinase erbB-4,Tyrosine kinase-type cell surface receptor HER4,4ICD,Avian erythroblastic leukemia viral oncogene homolog 4,Avian erythroblastic leukemia viral v erb b2 oncogene homolog 4,E4ICD,EC 2.7.10.1,ERBB4 intracellular domain,HER 4,human epidermal growth factor receptor 4,Mer4,MGC138404,Oncogene ERBB4,Receptor protein tyrosine kinase erbB 4 precursor,Receptor tyrosine protein kinase erbB 4,s80HER4,Tyrosine kinase type cell surface receptor HER4,v erb a avian erythroblastic leukemia viral oncogene homolog like 4,v erb a erythroblastic leukemia viral oncogene homolog 4,Verba avian erythroblastic leukemia viral oncogene homolog like 4,Verba erythroblastic leukemia viral oncogene homolog 4,v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian),VERBB2,V-ERB-B2 avian erythroblastic leukemia viral oncogene homolog 4,HER4/ErbB4, like other receptor tyrosine kinase family members, has four ectodomains, a single transmembrane domain and a cytoplasmic tail containing the active tyrosine kinase domain. By binding to neuregulins and/or EGF family ligands, ErbB4 forms either a homodimer or heterodimer with other ErbB family members, which results in receptor activation and signaling. ErbB4 is ubiquitously expressed with the highest expression occurring in brain and heart. The expression of ErbB4 in breast cancer, pediatric brain cancer and other types of carcinomas has been reported in research studies suggesting that ErbB4 expression is involved in both normal tissue development and carcinogenesis. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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UniProt
- Q15303
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
抗原
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