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Recombinant DcR1 抗体

The 兔 单克隆 anti-DcR1 antibody (Clone A716) (ABIN7828650) specifically detects DcR1 in WB 和 IF. The antibody is reactive with 人 samples.
产品编号 ABIN7828650
发货至: 中国
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Quick Overview for Recombinant DcR1 抗体 (ABIN7828650)

抗原

See all DcR1 (TNFRSF10C) 抗体
DcR1 (TNFRSF10C) (Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C))

抗体类型

Recombinant Antibody

适用

  • 89
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宿主

  • 67
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克隆类型

  • 59
  • 37
单克隆

标记

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This DcR1 antibody is un-conjugated

应用范围

  • 59
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Western Blotting (WB), Immunofluorescence (IF)

克隆位点

A716
  • 原理

    Recombinant DcR1 Monoclonal Antibody

    纯化方法

    Protein A purified

    亚型

    IgG, kappa
  • 应用备注

    WB 1:1000-1:2000,IF 1:50

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

    有效期

    12 months
  • 抗原

    DcR1 (TNFRSF10C) (Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C))

    别名

    DcR1

    背景

    DCR,UNQ,PRO,TRAILR,TRAIL-R,TNFRSF10C,CD263,DCR1,DCR1-TNFR,LIT,TRAIL-R3,TRAILR3,TRID,UNQ321,PRO366,DcR1,TRID,TNFRSF10c,Antagonist Decoy Receptor for TRAIL/Apo-2L,Decoy Receptor 1,Decoy TRAIL Receptor Without Death Domain,Lymphocyte Inhibitor of TRAIL,TNF-Related Apoptosis-Inducing Ligand Receptor 3,TRAIL Receptor 3,TRAIL Receptor Without an Intracellular Domain,Tumor Necrosis Factor Receptor Superfamily Member 10C,The tumor necrosis factor receptor family, which includes TNF-RI, Fas, DR3, DR4, DR5, and DR6, plays an important role in the regulation of apoptosis in various physiological systems.The receptors are activated by a family of cytokines that include TNF, FasL, and TNF-related apoptosis-inducing ligand (TRAIL). They are characterized by a highly conserved extracellular region containing cysteine-rich repeats and a conserved intracellular region of about 80 amino acids termed the death domain (DD). The DD is important for transducing the death signal by recruiting other DD containing adaptor proteins (FADD, TRADD, RIP) to the death-inducing signaling complex (DISC), resulting in activation of caspases.Death receptor signaling is also controlled by a family of decoy receptors (DcR1, DcR2, and DcR3) which lack a cytoplasmic DD and inhibit death receptor-mediated apoptosis by competing for ligand. Expression of decoy receptors provide a mechanism for certain types of cancer to regulate apoptosis and can contribute to chemosensitivity. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

    分子量

    Calculated MW: 27 kDa

    Observed MW: 27, 80-100 kDa The actual band is not consistent with the expectation.

    UniProt

    O14798

    途径

    Apoptosis
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