Recombinant TFF1 抗体
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北京 101111
Quick Overview for Recombinant TFF1 抗体 (ABIN7828641)
抗原
See all TFF1 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant TFF1/pS2 Monoclonal Antibody
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纯化方法
- Protein A purified
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免疫原
- Recombinant human TFF1/pS2 fragment
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亚型
- IgG, kappa
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应用备注
- WB 1:500-1:2000,IHC 1:50-1:100
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- TFF1 (Trefoil Factor 1 (TFF1))
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别名
- TFF1/pS2
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背景
- TFF,pNR,HPS,D21S,Protein Ps,Trefoil factor,TFF1,BCEI,D21S21,HP1.A,HPS2,pNR-2,pS2,Breast cancer estrogen-inducible protein,Polypeptide P1.A,Protein Ps2,Trefoil factor 1,TFF1/pS2 is a gastric peptide that is highly expressed by mucosal goblet cells of the stomach, where it is thought to play a role in maintaining the integrity of the epithelial layer of the mucosa through the regulation of cell-cell adhesion and cell migration. Research studies have shown that TFF1 functions as a tumor suppressor in the stomach as its expression is frequently lost in gastric carcinomas, largely due to promoter hypermethylation. Research studies have also demonstrated thatTFF1is a transcriptional target of estrogen receptor-α and that TFF1 expression in breast carcinoma may be used as a predictive biomarker for response to anti-estrogen therapy. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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分子量
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Calculated MW: 10 kDa
Observed MW: 13 kDa The actual band is not consistent with the expectation.
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UniProt
- P04155
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途径
- EGFR Signaling Pathway
抗原
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