Recombinant STING/TMEM173 抗体
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北京 101111
Quick Overview for Recombinant STING/TMEM173 抗体 (ABIN7828638)
抗原
See all STING/TMEM173 (TMEM173) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant STING Monoclonal Antibody
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纯化方法
- Protein A purified
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免疫原
- Recombinant human STING fragment
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亚型
- IgG, kappa
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anti-Transmembrane Protein 173 (TMEM173) (AA 170-379) antibody
TMEM173 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane Protein 173 (TMEM173) (AA 159-373) antibodyTMEM173 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane Protein 173 (TMEM173) antibodyTMEM173 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 4H8 unconjugated
anti-Transmembrane Protein 173 (TMEM173) (AA 284-316), (C-Term) antibodyTMEM173 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane Protein 173 (TMEM173) antibodyTMEM173 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane Protein 173 (TMEM173) (AA 311-340) antibodyTMEM173 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane Protein 173 (TMEM173) (AA 207-379) antibodyTMEM173 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane Protein 173 (TMEM173) (C-Term) antibodyTMEM173 适用: 人, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane Protein 173 (TMEM173) (C-Term) antibodyTMEM173 适用: 人, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane Protein 173 (TMEM173) antibodyTMEM173 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 2C9 unconjugated
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应用备注
- WB 1:500-1:2000,IHC 1:200-1:1000,IF 1:50
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))
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别名
- STING
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背景
- NET,TMEM,TMEM173,ERIS,MITA,MPYS,NET23,SAVI,STING,hMITA,hSTING,Mediator of IRF3 activation,Stimulator of interferon genes protein,STING1,endoplasmic reticulum IFN stimulator,Endoplasmic reticulum interferon stimulator,FLJ38577,Mitochondrial mediator of IRF3 activation,N terminal methionine proline tyrosine serine plasma membrane tetraspanner,Stimulator of interferon genes,TM173,Transmembrane protein 173,STING has several transmembrane domains, and is expressed in a variety of endothelial cells, epithelial cells and hematopoietic liver cells. STING participates in the DNA-mediated innate immune response. Non-CpG double-stranded DNA from viruses or bacteria binds to cGAS protein and is catalyzed to the second messenger cGAMP, then the dimerized STING binds to cGAMP and undergoes conformational changes. Through the autophagsome and the endoplasmic reticulum and the Golgi apparatus, it further enters the cytoplasm. During the period, it is ubiquitinated and recruited TBK1 protein, then phosphorylated, and then combined with IRF3, then IRF3 is phosphorylated and enters the nucleus to induce the expression of IFNs, etc. In conclusion, it can enhance the body's immune ability and kill bacteria, viruses and other pathogens to a greater extent. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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分子量
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Calculated MW: 42 kDa
Observed MW: 36 kDa The actual band is not consistent with the expectation.
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UniProt
- Q86WV6
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途径
- Activation of Innate immune Response
抗原
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