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Recombinant TPX2 抗体

This 兔 单克隆 antibody specifically detects TPX2 in WB, IHC, IF 和 FACS. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN7828630
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
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Quick Overview for Recombinant TPX2 抗体 (ABIN7828630)

抗原

See all TPX2 抗体
TPX2 (TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) (TPX2))

抗体类型

Recombinant Antibody

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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单克隆

标记

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This TPX2 antibody is un-conjugated

应用范围

  • 76
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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

克隆位点

A382
  • 原理

    Recombinant TPX2 Monoclonal Antibody

    纯化方法

    Protein A purified

    免疫原

    Recombinant human TPX2 fragment

    亚型

    IgG, kappa
  • 应用备注

    WB 1:500-1:1000,IHC 1:50-1:200,IF 1:50,FCM 1:50-1:100

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

    有效期

    12 months
  • 抗原

    TPX2 (TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) (TPX2))

    别名

    TPX2

    背景

    FLS,HCA,TPX,HCTP,REPP,GD:C20orf,DIL,DIL2,p100,DIL-2,HCTP4,FLS353,HCA519,REPP86,C20orf1,C20orf2,GD:C20orf1,TPX2,Chromosome 20 Open Reading Frame 1,Differentially expressed in cancerous and noncancerous lung cells 2,Differentially expressed in cancerous and non-cancerous lung cells 2,Differentially expressed in lung cells,Differentially expressed in lung cells 2,DIL 2,HCA 519,HCTP 4,Hepatocellular carcinoma associated antigen 519,Hepatocellular carcinoma-associated antigen 519,Preferentially expressed in colorectal cancer,Protein fls353,REPP 86,Restricted expression proliferation associated protein 100,Restricted expression proliferation-associated protein 100,Targeting protein for Xklp2,TPX 2,TPX2 microtubule associated homolog,TPX2 microtubule associated protein homolog,TPX2 microtubule nucleation factor,Spindle assembly factor required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules.Activates AURKA by promoting its autophosphorylation at 'Thr-288' and protects this residue against dephosphorylation. TPX2 is inactivated upon binding to importin-alpha .At the onset of mitosis, GOLGA2 interacts with importin-alpha, liberating TPX2 from importin-alpha, allowing TPX2 to activates AURKA kinase and stimulates local microtubule nucleation. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

    分子量

    Calculated MW: 86 kDa

    Observed MW: 100 kDa The actual band is not consistent with the expectation.

    UniProt

    Q9ULW0
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