Recombinant TPX2 抗体
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北京 101111
Quick Overview for Recombinant TPX2 抗体 (ABIN7828630)
抗原
See all TPX2 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant TPX2 Monoclonal Antibody
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纯化方法
- Protein A purified
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免疫原
- Recombinant human TPX2 fragment
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亚型
- IgG, kappa
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应用备注
- WB 1:500-1:1000,IHC 1:50-1:200,IF 1:50,FCM 1:50-1:100
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- TPX2 (TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) (TPX2))
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别名
- TPX2
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背景
- FLS,HCA,TPX,HCTP,REPP,GD:C20orf,DIL,DIL2,p100,DIL-2,HCTP4,FLS353,HCA519,REPP86,C20orf1,C20orf2,GD:C20orf1,TPX2,Chromosome 20 Open Reading Frame 1,Differentially expressed in cancerous and noncancerous lung cells 2,Differentially expressed in cancerous and non-cancerous lung cells 2,Differentially expressed in lung cells,Differentially expressed in lung cells 2,DIL 2,HCA 519,HCTP 4,Hepatocellular carcinoma associated antigen 519,Hepatocellular carcinoma-associated antigen 519,Preferentially expressed in colorectal cancer,Protein fls353,REPP 86,Restricted expression proliferation associated protein 100,Restricted expression proliferation-associated protein 100,Targeting protein for Xklp2,TPX 2,TPX2 microtubule associated homolog,TPX2 microtubule associated protein homolog,TPX2 microtubule nucleation factor,Spindle assembly factor required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules.Activates AURKA by promoting its autophosphorylation at 'Thr-288' and protects this residue against dephosphorylation. TPX2 is inactivated upon binding to importin-alpha .At the onset of mitosis, GOLGA2 interacts with importin-alpha, liberating TPX2 from importin-alpha, allowing TPX2 to activates AURKA kinase and stimulates local microtubule nucleation. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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分子量
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Calculated MW: 86 kDa
Observed MW: 100 kDa The actual band is not consistent with the expectation.
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UniProt
- Q9ULW0
抗原
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